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Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels. [electronic resource] by
- Dubé, G R
- Lehto, Sonya G
- Breese, Nicole M
- Baker, Scott J
- Wang, Xueqing
- Matulenko, Mark A
- Honoré, Prisca
- Stewart, Andrew O
- Moreland, Robert B
- Brioni, Jorge D
Producer: 20060105
In:
Pain vol. 117
Availability: No items available.
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Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors. [electronic resource] by
- Gomtsyan, Arthur
- Didomenico, Stanley
- Lee, Chih-Hung
- Matulenko, Mark A
- Kim, Ki
- Kowaluk, Elizabeth A
- Wismer, Carol T
- Mikusa, Joe
- Yu, Haixia
- Kohlhaas, Kathy
- Jarvis, Michael F
- Bhagwat, Shripad S
Producer: 20020904
In:
Journal of medicinal chemistry vol. 45
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6.
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Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists. [electronic resource] by
- Matulenko, Mark A
- Hakeem, Ahmed A
- Kolasa, Teodozyi
- Nakane, Masaki
- Terranova, Marc A
- Uchic, Marie E
- Miller, Loan N
- Chang, Renjie
- Donnelly-Roberts, Diana L
- Namovic, Marian T
- Moreland, Robert B
- Brioni, Jorge D
- Stewart, Andrew O
Producer: 20050111
In:
Bioorganic & medicinal chemistry vol. 12
Availability: No items available.
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Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes. [electronic resource] by
- Muchmore, Steven W
- Smith, Richard A
- Stewart, Andrew O
- Cowart, Marlon D
- Gomtsyan, Arthur
- Matulenko, Mark A
- Yu, Haixia
- Severin, Jean M
- Bhagwat, Shripad S
- Lee, Chih-Hung
- Kowaluk, Elizabeth A
- Jarvis, Michael F
- Jakob, Clarissa L
Producer: 20070119
In:
Journal of medicinal chemistry vol. 49
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A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. [electronic resource] by
- Zhang, Xu-Feng
- Shieh, Char-Chang
- Chapman, Mark L
- Matulenko, Mark A
- Hakeem, Ahmed H
- Atkinson, Robert N
- Kort, Michael E
- Marron, Brian E
- Joshi, Shailen
- Honore, Prisca
- Faltynek, Connie R
- Krafte, Douglas S
- Jarvis, Michael F
Producer: 20101014
In:
Neuropharmacology vol. 59
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Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand. [electronic resource] by
- Matulenko, Mark A
- Surber, Bruce
- Fan, Leimin
- Kolasa, Teodozyi
- Nakane, Masaki
- Terranova, Marc A
- Uchic, Marie E
- Miller, Loan N
- Chang, Renjie
- Donnelly-Roberts, Diana L
- Namovic, Marian T
- Moreland, Robert B
- Brioni, Jorge D
- Stewart, Andrew O
Producer: 20050404
In:
Bioorganic & medicinal chemistry letters vol. 14
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Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists. [electronic resource] by
- Wang, Xueqing
- Bhatia, Pramila A
- Daanen, Jerome F
- Latsaw, Steve P
- Rohde, Jeffrey
- Kolasa, Teodozyi
- Hakeem, Ahmed A
- Matulenko, Mark A
- Nakane, Masaki
- Uchic, Marie E
- Miller, Loan N
- Chang, Renjie
- Moreland, Robert B
- Brioni, Jorge D
- Stewart, Andrew O
Producer: 20050923
In:
Bioorganic & medicinal chemistry vol. 13
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Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain. [electronic resource] by
- Frost, Jennifer M
- DeGoey, David A
- Shi, Lei
- Gum, Rebecca J
- Fricano, Meagan M
- Lundgaard, Greta L
- El-Kouhen, Odile F
- Hsieh, Gin C
- Neelands, Torben
- Matulenko, Mark A
- Daanen, Jerome F
- Pai, Madhavi
- Ghoreishi-Haack, Nayereh
- Zhan, Cenchen
- Zhang, Xu-Feng
- Kort, Michael E
Producer: 20160927
In:
Journal of medicinal chemistry vol. 59
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12.
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Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning. [electronic resource] by
- Stewart, Andrew O
- Cowart, Marlon D
- Moreland, Robert B
- Latshaw, Steve P
- Matulenko, Mark A
- Bhatia, Pramila A
- Wang, Xueqing
- Daanen, Jerome F
- Nelson, Sherry L
- Terranova, Marc A
- Namovic, Marian T
- Donnelly-Roberts, Diana L
- Miller, Loan N
- Nakane, Masaki
- Sullivan, James P
- Brioni, Jorge D
Producer: 20040520
In:
Journal of medicinal chemistry vol. 47
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4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors. [electronic resource] by
- Matulenko, Mark A
- Paight, Ernest S
- Frey, Robin R
- Gomtsyan, Arthur
- DiDomenico, Stanley
- Jiang, Meiqun
- Lee, Chih-Hung
- Stewart, Andrew O
- Yu, Haixia
- Kohlhaas, Kathy L
- Alexander, Karen M
- McGaraughty, Steve
- Mikusa, Joseph
- Marsh, Kennan C
- Muchmore, Steven W
- Jakob, Clarissa L
- Kowaluk, Elizabeth A
- Jarvis, Michael F
- Bhagwat, Shripad S
Producer: 20070403
In:
Bioorganic & medicinal chemistry vol. 15
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1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction. [electronic resource] by
- Kolasa, Teodozyj
- Matulenko, Mark A
- Hakeem, Ahmed A
- Patel, Meena V
- Mortell, Kathleen
- Bhatia, Pramila
- Henry, Rodger
- Nakane, Masaki
- Hsieh, Gin C
- Terranova, Marc A
- Uchic, Marie E
- Miller, Loan N
- Chang, Renje
- Donnelly-Roberts, Diana L
- Namovic, Marian T
- Hollingsworth, Peter R
- Martino, Brenda
- El Kouhen, Odile
- Marsh, Kennan C
- Wetter, Jill M
- Moreland, Robert B
- Brioni, Jorge D
- Stewart, Andrew O
Producer: 20061003
In:
Journal of medicinal chemistry vol. 49
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15.
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5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors. [electronic resource] by
- Matulenko, Mark A
- Lee, Chih-Hung
- Jiang, Meiqun
- Frey, Robin R
- Cowart, Marlon D
- Bayburt, Erol K
- Didomenico, Stanley
- Gfesser, Gregory A
- Gomtsyan, Arthur
- Zheng, Guo Zhu
- McKie, Jeffery A
- Stewart, Andrew O
- Yu, Haixia
- Kohlhaas, Kathy L
- Alexander, Karen M
- McGaraughty, Steve
- Wismer, Carol T
- Mikusa, Joseph
- Marsh, Kennan C
- Snyder, Ronald D
- Diehl, Marilyn S
- Kowaluk, Elizabeth A
- Jarvis, Michael F
- Bhagwat, Shripad S
Producer: 20051121
In:
Bioorganic & medicinal chemistry vol. 13
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16.
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Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530). [electronic resource] by
- Wagner, Rolf
- Randolph, John T
- Patel, Sachin V
- Nelson, Lissa
- Matulenko, Mark A
- Keddy, Ryan
- Pratt, John K
- Liu, Dachun
- Krueger, A Chris
- Donner, Pamela L
- Hutchinson, Douglas K
- Flentge, Charles
- Betebenner, David
- Rockway, Todd
- Maring, Clarence J
- Ng, Teresa I
- Krishnan, Preethi
- Pilot-Matias, Tami
- Collins, Christine
- Panchal, Neeta
- Reisch, Thomas
- Dekhtyar, Tatyana
- Mondal, Rubina
- Stolarik, DeAnne F
- Gao, Yi
- Gao, Wenqing
- Beno, David A
- Kati, Warren M
Producer: 20190528
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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17.
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Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. [electronic resource] by
- Kort, Michael E
- Atkinson, Robert N
- Thomas, James B
- Drizin, Irene
- Johnson, Matthew S
- Secrest, Matthew A
- Gregg, Robert J
- Scanio, Marc J C
- Shi, Lei
- Hakeem, Ahmed H
- Matulenko, Mark A
- Chapman, Mark L
- Krambis, Michael J
- Liu, Dong
- Shieh, Char-Chang
- Zhang, XuFeng
- Simler, Gricelda
- Mikusa, Joseph P
- Zhong, Chengmin
- Joshi, Shailen
- Honore, Prisca
- Roeloffs, Rosemarie
- Werness, Stephen
- Antonio, Brett
- Marsh, Kennan C
- Faltynek, Connie R
- Krafte, Douglas S
- Jarvis, Michael F
- Marron, Brian E
Producer: 20110329
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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18.
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Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction. [electronic resource] by
- Patel, Meena V
- Kolasa, Teodozyj
- Mortell, Kathleen
- Matulenko, Mark A
- Hakeem, Ahmed A
- Rohde, Jeffrey J
- Nelson, Sherry L
- Cowart, Marlon D
- Nakane, Masaki
- Miller, Loan N
- Uchic, Marie E
- Terranova, Marc A
- El-Kouhen, Odile F
- Donnelly-Roberts, Diana L
- Namovic, Marian T
- Hollingsworth, Peter R
- Chang, Renjie
- Martino, Brenda R
- Wetter, Jill M
- Marsh, Kennan C
- Martin, Ruth
- Darbyshire, John F
- Gintant, Gary
- Hsieh, Gin C
- Moreland, Robert B
- Sullivan, James P
- Brioni, Jorge D
- Stewart, Andrew O
Producer: 20070223
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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