Computational design of anti-CRISPR proteins with improved inhibition potency. [electronic resource]
Producer: 20201008Description: 725-730 p. digitalISSN:- 1552-4469
- Amino Acid Sequence
- CRISPR-Associated Protein 9 -- genetics
- CRISPR-Cas Systems
- Cell Line, Tumor
- Clustered Regularly Interspaced Short Palindromic Repeats
- Gene Editing -- methods
- Genome, Human
- HEK293 Cells
- Hepatocytes -- cytology
- Humans
- MicroRNAs -- genetics
- Models, Molecular
- Mutagenesis, Insertional
- Neisseria meningitidis -- enzymology
- Plasmids -- chemistry
- Protein Domains
- Protein Engineering -- methods
- Protein Structure, Secondary
- RNA, Guide, CRISPR-Cas Systems -- genetics
- Staphylococcus aureus -- enzymology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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