Computational design of anti-CRISPR proteins with improved inhibition potency.
Mathony, Jan
Computational design of anti-CRISPR proteins with improved inhibition potency. [electronic resource] - Nature chemical biology Jul 2020 - 725-730 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1552-4469
10.1038/s41589-020-0518-9 doi
Amino Acid Sequence
CRISPR-Associated Protein 9--genetics
CRISPR-Cas Systems
Cell Line, Tumor
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Editing--methods
Genome, Human
HEK293 Cells
Hepatocytes--cytology
Humans
MicroRNAs--genetics
Models, Molecular
Mutagenesis, Insertional
Neisseria meningitidis--enzymology
Plasmids--chemistry
Protein Domains
Protein Engineering--methods
Protein Structure, Secondary
RNA, Guide, CRISPR-Cas Systems--genetics
Staphylococcus aureus--enzymology
Computational design of anti-CRISPR proteins with improved inhibition potency. [electronic resource] - Nature chemical biology Jul 2020 - 725-730 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1552-4469
10.1038/s41589-020-0518-9 doi
Amino Acid Sequence
CRISPR-Associated Protein 9--genetics
CRISPR-Cas Systems
Cell Line, Tumor
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Editing--methods
Genome, Human
HEK293 Cells
Hepatocytes--cytology
Humans
MicroRNAs--genetics
Models, Molecular
Mutagenesis, Insertional
Neisseria meningitidis--enzymology
Plasmids--chemistry
Protein Domains
Protein Engineering--methods
Protein Structure, Secondary
RNA, Guide, CRISPR-Cas Systems--genetics
Staphylococcus aureus--enzymology