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Expeditive syntheses of functionalized pentahelicenes and NC-AFM on Ag(001). [electronic resource] by
- Goretta, Sarah
- Tasciotti, Christelle
- Mathieu, Simon
- Smet, Mario
- Maes, Wouter
- Chabre, Yoann M
- Dehaen, Wim
- Giasson, Richard
- Raimundo, Jean-Manuel
- Henry, Claude R
- Barth, Clemens
- Gingras, Marc
Producer: 20090923
In:
Organic letters vol. 11
Availability: No items available.
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8.
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Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors. [electronic resource] by
- Lee, Wendy
- Crawford, James J
- Aliagas, Ignacio
- Murray, Lesley J
- Tay, Suzanne
- Wang, Weiru
- Heise, Christopher E
- Hoeflich, Klaus P
- La, Hank
- Mathieu, Simon
- Mintzer, Robert
- Ramaswamy, Sreemathy
- Rouge, Lionel
- Rudolph, Joachim
Producer: 20170619
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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9.
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"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors. [electronic resource] by
- Chen, Xin
- Giraldes, John
- Sprague, Elizabeth R
- Shakya, Subarna
- Chen, Zhuoliang
- Wang, Yaping
- Joud, Carol
- Mathieu, Simon
- Chen, Christine Hiu-Tung
- Straub, Christopher
- Duca, Jose
- Hurov, Kristen
- Yuan, Yanqiu
- Shao, Wenlin
- Touré, B Barry
Producer: 20170807
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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10.
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Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series. [electronic resource] by
- Rudolph, Joachim
- Aliagas, Ignacio
- Crawford, James J
- Mathieu, Simon
- Lee, Wendy
- Chao, Qi
- Dong, Ping
- Rouge, Lionel
- Wang, Weiru
- Heise, Christopher
- Murray, Lesley J
- La, Hank
- Liu, Yanzhou
- Manning, Gerard
- Diederich, François
- Hoeflich, Klaus P
Producer: 20150623
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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11.
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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase. [electronic resource] by
- Wenglowsky, Steve
- Ren, Li
- Grina, Jonas
- Hansen, Joshua D
- Laird, Ellen R
- Moreno, David
- Dinkel, Victoria
- Gloor, Susan L
- Hastings, Gregg
- Rana, Sumeet
- Rasor, Kevin
- Sturgis, Hillary L
- Voegtli, Walter C
- Vigers, Guy
- Willis, Brandon
- Mathieu, Simon
- Rudolph, Joachim
Producer: 20141020
In:
Bioorganic & medicinal chemistry letters vol. 24
Availability: No items available.
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12.
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The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase. [electronic resource] by
- Ren, Li
- Ahrendt, Kateri A
- Grina, Jonas
- Laird, Ellen R
- Buckmelter, Alex J
- Hansen, Joshua D
- Newhouse, Brad
- Moreno, David
- Wenglowsky, Steve
- Dinkel, Victoria
- Gloor, Susan L
- Hastings, Gregg
- Rana, Sumeet
- Rasor, Kevin
- Risom, Tyler
- Sturgis, Hillary L
- Voegtli, Walter C
- Mathieu, Simon
Producer: 20120910
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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13.
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Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships. [electronic resource] by
- Wenglowsky, Steve
- Ahrendt, Kateri A
- Buckmelter, Alex J
- Feng, Bainian
- Gloor, Susan L
- Gradl, Stefan
- Grina, Jonas
- Hansen, Joshua D
- Laird, Ellen R
- Lunghofer, Paul
- Mathieu, Simon
- Moreno, David
- Newhouse, Brad
- Ren, Li
- Risom, Tyler
- Rudolph, Joachim
- Seo, Jeongbeob
- Sturgis, Hillary L
- Voegtli, Walter C
- Wen, Zhaoyang
Producer: 20111219
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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14.
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Rational design of phosphoinositide 3-kinase α inhibitors that exhibit selectivity over the phosphoinositide 3-kinase β isoform. [electronic resource] by
- Heffron, Timothy P
- Wei, Binqing
- Olivero, Alan
- Staben, Steven T
- Tsui, Vickie
- Do, Steven
- Dotson, Jennafer
- Folkes, Adrian J
- Goldsmith, Paul
- Goldsmith, Richard
- Gunzner, Janet
- Lesnick, John
- Lewis, Cristina
- Mathieu, Simon
- Nonomiya, Jim
- Shuttleworth, Stephen
- Sutherlin, Daniel P
- Wan, Nan Chi
- Wang, Shumei
- Wiesmann, Christian
- Zhu, Bing-Yan
Producer: 20120207
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
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15.
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Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor. [electronic resource] by
- Heffron, Timothy P
- Berry, Megan
- Castanedo, Georgette
- Chang, Christine
- Chuckowree, Irina
- Dotson, Jennafer
- Folkes, Adrian
- Gunzner, Janet
- Lesnick, John D
- Lewis, Cristina
- Mathieu, Simon
- Nonomiya, Jim
- Olivero, Alan
- Pang, Jodie
- Peterson, David
- Salphati, Laurent
- Sampath, Deepak
- Sideris, Steve
- Sutherlin, Daniel P
- Tsui, Vickie
- Wan, Nan Chi
- Wang, Shumei
- Wong, Susan
- Zhu, Bing-Yan
Producer: 20100812
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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16.
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Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. [electronic resource] by
- Touré, B Barry
- Giraldes, John
- Smith, Troy
- Sprague, Elizabeth R
- Wang, Yaping
- Mathieu, Simon
- Chen, Zhuoliang
- Mishina, Yuji
- Feng, Yun
- Yan-Neale, Yan
- Shakya, Subarna
- Chen, Dongshu
- Meyer, Matthew
- Puleo, David
- Brazell, J Tres
- Straub, Christopher
- Sage, David
- Wright, Kirk
- Yuan, Yanqiu
- Chen, Xin
- Duca, Jose
- Kim, Sean
- Tian, Li
- Martin, Eric
- Hurov, Kristen
- Shao, Wenlin
Producer: 20170529
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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17.
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Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer. [electronic resource] by
- Sutherlin, Daniel P
- Sampath, Deepak
- Berry, Megan
- Castanedo, Georgette
- Chang, Zhigang
- Chuckowree, Irina
- Dotson, Jenna
- Folkes, Adrian
- Friedman, Lori
- Goldsmith, Richard
- Heffron, Tim
- Lee, Leslie
- Lesnick, John
- Lewis, Cristina
- Mathieu, Simon
- Nonomiya, Jim
- Olivero, Alan
- Pang, Jodie
- Prior, Wei Wei
- Salphati, Laurent
- Sideris, Steve
- Tian, Qingping
- Tsui, Vickie
- Wan, Nan Chi
- Wang, Shumei
- Wiesmann, Christian
- Wong, Susan
- Zhu, Bing-Yan
Producer: 20100312
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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18.
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Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties. [electronic resource] by
- Mathieu, Simon
- Gradl, Stefan N
- Ren, Li
- Wen, Zhaoyang
- Aliagas, Ignacio
- Gunzner-Toste, Janet
- Lee, Wendy
- Pulk, Rebecca
- Zhao, Guiling
- Alicke, Bruno
- Boggs, Jason W
- Buckmelter, Alex J
- Choo, Edna F
- Dinkel, Victoria
- Gloor, Susan L
- Gould, Stephen E
- Hansen, Joshua D
- Hastings, Gregg
- Hatzivassiliou, Georgia
- Laird, Ellen R
- Moreno, David
- Ran, Yingqing
- Voegtli, Walter C
- Wenglowsky, Steve
- Grina, Jonas
- Rudolph, Joachim
Producer: 20120727
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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19.
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Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer. [electronic resource] by
- Sutherlin, Daniel P
- Bao, Linda
- Berry, Megan
- Castanedo, Georgette
- Chuckowree, Irina
- Dotson, Jenna
- Folks, Adrian
- Friedman, Lori
- Goldsmith, Richard
- Gunzner, Janet
- Heffron, Timothy
- Lesnick, John
- Lewis, Cristina
- Mathieu, Simon
- Murray, Jeremy
- Nonomiya, Jim
- Pang, Jodie
- Pegg, Niel
- Prior, Wei Wei
- Rouge, Lionel
- Salphati, Laurent
- Sampath, Deepak
- Tian, Qingping
- Tsui, Vickie
- Wan, Nan Chi
- Wang, Shumei
- Wei, Binqing
- Wiesmann, Christian
- Wu, Ping
- Zhu, Bing-Yan
- Olivero, Alan
Producer: 20120207
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
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20.
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Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. [electronic resource] by
- Papillon, Julien P N
- Nakajima, Katsumasa
- Adair, Christopher D
- Hempel, Jonathan
- Jouk, Andriana O
- Karki, Rajeshri G
- Mathieu, Simon
- Möbitz, Henrik
- Ntaganda, Rukundo
- Smith, Troy
- Visser, Michael
- Hill, Susan E
- Hurtado, Felipe Kellermann
- Chenail, Gregg
- Bhang, Hyo-Eun C
- Bric, Anka
- Xiang, Kay
- Bushold, Geoffrey
- Gilbert, Tamara
- Vattay, Anthony
- Dooley, Julie
- Costa, Emily A
- Park, Isabel
- Li, Ailing
- Farley, David
- Lounkine, Eugen
- Yue, Q Kimberley
- Xie, Xiaoling
- Zhu, Xiaoping
- Kulathila, Raviraj
- King, Daniel
- Hu, Tiancen
- Vulic, Katarina
- Cantwell, John
- Luu, Catherine
- Jagani, Zainab
Producer: 20190930
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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