Results
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1.
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Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. [electronic resource] by
- Mathes, Brian M
- Hudziak, Kevin J
- Schaus, John M
- Xu, Yao-Chang
- Nelson, David L
- Wainscott, David B
- Nutter, Suzanne E
- Gough, Wendy H
- Branchek, Theresa A
- Zgombick, John M
- Filla, Sandra A
Producer: 20040827
In:
Bioorganic & medicinal chemistry letters vol. 14
Availability: No items available.
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2.
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Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. [electronic resource] by
- Filla, Sandra A
- Mathes, Brian M
- Johnson, Kirk W
- Phebus, Lee A
- Cohen, Marlene L
- Nelson, David L
- Zgombick, John M
- Erickson, Jon A
- Schenck, Kathryn W
- Wainscott, David B
- Branchek, Theresa A
- Schaus, John M
Producer: 20030807
In:
Journal of medicinal chemistry vol. 46
Availability: No items available.
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3.
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Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. [electronic resource] by
- Zhang, Deyi
- Blanco, Maria-Jesus
- Ying, Bai-Ping
- Kohlman, Daniel
- Liang, Sidney X
- Victor, Frantz
- Chen, Qi
- Krushinski, Joseph
- Filla, Sandra A
- Hudziak, Kevin J
- Mathes, Brian M
- Cohen, Michael P
- Zacherl, DeAnna
- Nelson, David L G
- Wainscott, David B
- Nutter, Suzanne E
- Gough, Wendy H
- Schaus, John M
- Xu, Yao-Chang
Producer: 20160524
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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4.
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Preparation and biological evaluation of conformationally constrained BACE1 inhibitors. [electronic resource] by
- Winneroski, Leonard L
- Schiffler, Matthew A
- Erickson, Jon A
- May, Patrick C
- Monk, Scott A
- Timm, David E
- Audia, James E
- Beck, James P
- Boggs, Leonard N
- Borders, Anthony R
- Boyer, Robert D
- Brier, Richard A
- Hudziak, Kevin J
- Klimkowski, Valentine J
- Garcia Losada, Pablo
- Mathes, Brian M
- Stout, Stephanie L
- Watson, Brian M
- Mergott, Dustin J
Producer: 20160226
In:
Bioorganic & medicinal chemistry vol. 23
Availability: No items available.
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5.
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Ethyl (3S,4aR,6S,8aR)-6-(4-ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso-quinoline-3-carboxylic ester: a prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraine. [electronic resource] by
- Filla, Sandra A
- Winter, Mark A
- Johnson, Kirk W
- Bleakman, David
- Bell, Michael G
- Bleisch, Thomas J
- Castaño, Ana M
- Clemens-Smith, Amy
- del Prado, Miriam
- Dieckman, Donna K
- Dominguez, Esteban
- Escribano, Ana
- Ho, Ken H
- Hudziak, Kevin J
- Katofiasc, Mary A
- Martinez-Perez, Jose A
- Mateo, Ana
- Mathes, Brian M
- Mattiuz, Edward L
- Ogden, Ann Marie L
- Phebus, Lee A
- Stack, Douglas R
- Stratford, Robert E
- Ornstein, Paul L
Producer: 20021021
In:
Journal of medicinal chemistry vol. 45
Availability: No items available.
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6.
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Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor. [electronic resource] by
- May, Patrick C
- Dean, Robert A
- Lowe, Stephen L
- Martenyi, Ferenc
- Sheehan, Scott M
- Boggs, Leonard N
- Monk, Scott A
- Mathes, Brian M
- Mergott, Dustin J
- Watson, Brian M
- Stout, Stephanie L
- Timm, David E
- Smith Labell, Elizabeth
- Gonzales, Celedon R
- Nakano, Masako
- Jhee, Stanford S
- Yen, Mark
- Ereshefsky, Larry
- Lindstrom, Terry D
- Calligaro, David O
- Cocke, Patrick J
- Greg Hall, D
- Friedrich, Stuart
- Citron, Martin
- Audia, James E
Producer: 20120112
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 31
Availability: No items available.
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7.
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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints. [electronic resource] by
- Winneroski, Leonard L
- Erickson, Jon A
- Green, Steven J
- Lopez, Jose E
- Stout, Stephanie L
- Porter, Warren J
- Timm, David E
- Audia, James E
- Barberis, Mario
- Beck, James P
- Boggs, Leonard N
- Borders, Anthony R
- Boyer, Robert D
- Brier, Richard A
- Hembre, Erik J
- Hendle, Jörg
- Garcia-Losada, Pablo
- Minguez, Jose Miguel
- Mathes, Brian M
- May, Patrick C
- Monk, Scott A
- Rankovic, Zoran
- Shi, Yuan
- Watson, Brian M
- Yang, Zhixiang
- Mergott, Dustin J
Producer: 20210127
In:
Bioorganic & medicinal chemistry vol. 28
Availability: No items available.
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8.
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GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models. [electronic resource] by
- Martinez-Perez, Jose A
- Iyengar, Smriti
- Shannon, Harlan E
- Bleakman, David
- Alt, Andrew
- Arnold, Brian M
- Bell, Michael G
- Bleisch, Thomas J
- Castaño, Ana M
- Del Prado, Miriam
- Dominguez, Esteban
- Escribano, Ana M
- Filla, Sandra A
- Ho, Ken H
- Hudziak, Kevin J
- Jones, Carrie K
- Mateo, Ana
- Mathes, Brian M
- Mattiuz, Edward L
- Ogden, Ann Marie L
- Simmons, Rosa Maria A
- Stack, Douglas R
- Stratford, Robert E
- Winter, Mark A
- Wu, Zhipei
- Ornstein, Paul L
Producer: 20140817
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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9.
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GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy. [electronic resource] by
- Martinez-Perez, Jose A
- Iyengar, Smriti
- Shannon, Harlan E
- Bleakman, David
- Alt, Andrew
- Clawson, David K
- Arnold, Brian M
- Bell, Michael G
- Bleisch, Thomas J
- Castaño, Ana M
- Del Prado, Miriam
- Dominguez, Esteban
- Escribano, Ana M
- Filla, Sandra A
- Ho, Ken H
- Hudziak, Kevin J
- Jones, Carrie K
- Mateo, Ana
- Mathes, Brian M
- Mattiuz, Edward L
- Ogden, Ann Marie L
- Simmons, Rosa Maria A
- Stack, Douglas R
- Stratford, Robert E
- Winter, Mark A
- Wu, Zhipei
- Ornstein, Paul L
Producer: 20140817
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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10.
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Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain. [electronic resource] by
- Dominguez, Esteban
- Iyengar, Smriti
- Shannon, Harlan E
- Bleakman, David
- Alt, Andrew
- Arnold, Brian M
- Bell, Michael G
- Bleisch, Thomas J
- Buckmaster, Jennifer L
- Castano, Ana M
- Del Prado, Miriam
- Escribano, Ana
- Filla, Sandra A
- Ho, Ken H
- Hudziak, Kevin J
- Jones, Carrie K
- Martinez-Perez, Jose A
- Mateo, Ana
- Mathes, Brian M
- Mattiuz, Edward L
- Ogden, Ann Marie L
- Simmons, Rosa Maria A
- Stack, Douglas R
- Stratford, Robert E
- Winter, Mark A
- Wu, Zhipei
- Ornstein, Paul L
Producer: 20050823
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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11.
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The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans. [electronic resource] by
- May, Patrick C
- Willis, Brian A
- Lowe, Stephen L
- Dean, Robert A
- Monk, Scott A
- Cocke, Patrick J
- Audia, James E
- Boggs, Leonard N
- Borders, Anthony R
- Brier, Richard A
- Calligaro, David O
- Day, Theresa A
- Ereshefsky, Larry
- Erickson, Jon A
- Gevorkyan, Hykop
- Gonzales, Celedon R
- James, Douglas E
- Jhee, Stanford S
- Komjathy, Steven F
- Li, Linglin
- Lindstrom, Terry D
- Mathes, Brian M
- Martényi, Ferenc
- Sheehan, Scott M
- Stout, Stephanie L
- Timm, David E
- Vaught, Grant M
- Watson, Brian M
- Winneroski, Leonard L
- Yang, Zhixiang
- Mergott, Dustin J
Producer: 20150324
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 35
Availability: No items available.
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