Inhibition of tyrosine kinases blocks adhesion-induced T-cell coactivation without interfering with T-cell adhesion to endothelial cell-surface ligands. [electronic resource]
Producer: 20030804Description: 31-43 p. digitalISSN:- 0360-3997
- Antibodies, Monoclonal -- pharmacology
- CD3 Complex -- immunology
- Cell Adhesion -- drug effects
- Cell Adhesion Molecules -- metabolism
- Dose-Response Relationship, Drug
- Endothelium -- chemistry
- Enzyme Inhibitors -- pharmacology
- Humans
- Interleukin-2 -- biosynthesis
- Lymphocyte Activation -- drug effects
- Mitogen-Activated Protein Kinase Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Signal Transduction
- T-Lymphocytes -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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