Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway. [electronic resource]
Producer: 20160208Description: 8996 p. digitalISSN:- 2045-2322
- Adult
- Aged
- Aged, 80 and over
- Anthocyanins -- pharmacology
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- metabolism
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Female
- Glucosides -- pharmacology
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- metabolism
- Male
- Middle Aged
- Oxidation-Reduction
- Phosphorylation
- Plant Extracts -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Vaccinium myrtillus -- chemistry
- bcl-Associated Death Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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