Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway.

Alhosin, Mahmoud

Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway. [electronic resource] - Scientific reports Mar 2015 - 8996 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep08996 doi


Adult
Aged
Aged, 80 and over
Anthocyanins--pharmacology
Apoptosis--drug effects
Apoptosis Regulatory Proteins--metabolism
Caspase 3--metabolism
Cell Line, Tumor
Female
Glucosides--pharmacology
Humans
Leukemia, Lymphocytic, Chronic, B-Cell--metabolism
Male
Middle Aged
Oxidation-Reduction
Phosphorylation
Plant Extracts--pharmacology
Proto-Oncogene Proteins c-bcl-2--metabolism
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Vaccinium myrtillus--chemistry
bcl-Associated Death Protein--metabolism