Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3. [electronic resource]
Producer: 20110801Description: 3549-63 p. digitalISSN:- 1520-4804
- Active Transport, Cell Nucleus
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Chemistry, Pharmaceutical -- methods
- Drug Design
- Drug Screening Assays, Antitumor
- Humans
- Kinetics
- Models, Chemical
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Prodrugs
- Protein Structure, Tertiary
- STAT3 Transcription Factor -- chemistry
- Signal Transduction
- src Homology Domains
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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