TGF-beta1-induced thrombospondin-1 expression through the p38 MAPK pathway is abolished by fluvastatin in human coronary artery smooth muscle cells. [electronic resource]
Producer: 20060829Description: 469-75 p. digitalISSN:- 1537-1891
- Adult
- Cells, Cultured
- Coronary Restenosis -- prevention & control
- Coronary Vessels -- drug effects
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Fatty Acids, Monounsaturated -- pharmacology
- Fluvastatin
- Gene Expression Regulation
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Imidazoles -- pharmacology
- Indoles -- pharmacology
- MAP Kinase Signaling System
- Male
- Muscle, Smooth, Vascular -- drug effects
- Myocytes, Smooth Muscle -- drug effects
- Phosphorylation
- Pyridines -- pharmacology
- RNA, Messenger -- metabolism
- Thrombospondin 1 -- genetics
- Transforming Growth Factor beta -- pharmacology
- Transforming Growth Factor beta1
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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