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Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds. [electronic resource] by
- Zientek, Michael
- Miller, Howard
- Smith, Danielle
- Dunklee, Mary Beth
- Heinle, Lance
- Thurston, Archie
- Lee, Caroline
- Hyland, Ruth
- Fahmi, Odette
- Burdette, Douglas
Producer: 20090202
In:
Journal of pharmacological and toxicological methods vol. 58
Availability: No items available.
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Comparison of different algorithms for predicting clinical drug-drug interactions, based on the use of CYP3A4 in vitro data: predictions of compounds as precipitants of interaction. [electronic resource] by
- Fahmi, Odette A
- Hurst, Susan
- Plowchalk, David
- Cook, Jack
- Guo, Feng
- Youdim, Kuresh
- Dickins, Maurice
- Phipps, Alex
- Darekar, Amanda
- Hyland, Ruth
- Obach, R Scott
Producer: 20091019
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 37
Availability: No items available.
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Critical review of preclinical approaches to investigate cytochrome p450-mediated therapeutic protein drug-drug interactions and recommendations for best practices: a white paper. [electronic resource] by
- Evers, Raymond
- Dallas, Shannon
- Dickmann, Leslie J
- Fahmi, Odette A
- Kenny, Jane R
- Kraynov, Eugenia
- Nguyen, Theresa
- Patel, Aarti H
- Slatter, J Greg
- Zhang, Lei
Producer: 20140401
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 41
Availability: No items available.
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How current understanding of clearance mechanisms and pharmacodynamics of therapeutic proteins can be applied for evaluation of their drug-drug interaction potential. [electronic resource] by
- Kraynov, Eugenia
- Martin, Steven W
- Hurst, Susan
- Fahmi, Odette A
- Dowty, Martin
- Cronenberger, Carol
- Loi, Cho-Ming
- Kuang, Bing
- Fields, Owen
- Fountain, Scott
- Awwad, Michel
- Wang, Diane
Producer: 20120329
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 39
Availability: No items available.
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Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction. [electronic resource] by
- Youdim, Kuresh A
- Zayed, Aref
- Dickins, Maurice
- Phipps, Alex
- Griffiths, Michelle
- Darekar, Amanda
- Hyland, Ruth
- Fahmi, Odette
- Hurst, Susan
- Plowchalk, David R
- Cook, Jack
- Guo, Feng
- Obach, R Scott
Producer: 20080723
In:
British journal of clinical pharmacology vol. 65
Availability: No items available.
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The time to move cytochrome p450 induction into mainstream pharmacology is long overdue. [electronic resource] by
- Smith, Dennis A
- Dickins, Maurice
- Fahmi, Odette A
- Iwasaki, Kazuhide
- Lee, Caroline
- Obach, R Scott
- Padbury, Guy
- De Morais, Sonia M
- Ripp, Sharon L
- Stevens, Jeff
- Voorman, Richard
- Youdim, Kuresh
Producer: 20070606
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 35
Availability: No items available.
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Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome. [electronic resource] by
- Dong, Jennifer Q
- Gosset, James R
- Fahmi, Odette A
- Lin, Zhiwu
- Chabot, Jeffrey R
- Terra, Steven G
- Le, Vu
- Chidsey, Kristin
- Nouri, Parya
- Kim, Albert
- Buckbinder, Leonard
- Kalgutkar, Amit S
Producer: 20170420
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 45
Availability: No items available.
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