Selective alkylation and acylation of alpha and epsilon amino groups with PEG in a somatostatin analogue: tailored chemistry for optimized bioconjugates. [electronic resource]
Producer: 20030516Description: 1238-43 p. digitalISSN:- 1043-1802
- Acylation
- Alkylation
- Amino Acid Sequence
- Animals
- Cells, Cultured
- Chromatography, High Pressure Liquid
- Circular Dichroism
- Growth Hormone -- metabolism
- Inhibitory Concentration 50
- Male
- Molecular Structure
- Pituitary Gland, Anterior -- cytology
- Polyethylene Glycols -- chemistry
- Rats
- Somatostatin -- analogs & derivatives
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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