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High molecular weight chitosan derivative polymeric micelles encapsulating superparamagnetic iron oxide for tumor-targeted magnetic resonance imaging. [electronic resource] by
- Xiao, Yunbin
- Lin, Zuan Tao
- Chen, Yanmei
- Wang, He
- Deng, Ya Li
- Le, D Elizabeth
- Bin, Jianguo
- Li, Meiyu
- Liao, Yulin
- Liu, Yili
- Jiang, Gangbiao
- Bin, Jianping
Producer: 20160509
In:
International journal of nanomedicine vol. 10
Availability: No items available.
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9.
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Characterization of the CHK1 allosteric inhibitor binding site. [electronic resource] by
- Vanderpool, Darin
- Johnson, Ted O
- Ping, Chen
- Bergqvist, Simon
- Alton, Gordon
- Phonephaly, Soneprasith
- Rui, Eugene
- Luo, Chun
- Deng, Ya-Li
- Grant, Stephan
- Quenzer, Terri
- Margosiak, Steve
- Register, James
- Brown, Ed
- Ermolieff, Jacques
Producer: 20091102
In:
Biochemistry vol. 48
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10.
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Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction. [electronic resource] by
- Cardoso, Rosa
- Love, Robert
- Nilsson, Carol L
- Bergqvist, Simon
- Nowlin, Dawn
- Yan, Jiangli
- Liu, Kevin K-C
- Zhu, Jing
- Chen, Ping
- Deng, Ya-Li
- Dyson, H Jane
- Greig, Michael J
- Brooun, Alexei
Producer: 20130429
In:
Protein science : a publication of the Protein Society vol. 21
Availability: No items available.
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11.
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Narrowband Organic Light-Emitting Diodes for Fluorescence Microscopy and Calcium Imaging. [electronic resource] by
- Murawski, Caroline
- Mischok, Andreas
- Booth, Jonathan
- Kumar, Jothi Dinesh
- Archer, Emily
- Tropf, Laura
- Keum, Chang-Min
- Deng, Ya-Li
- Yoshida, Kou
- Samuel, Ifor D W
- Schubert, Marcel
- Pulver, Stefan R
- Gather, Malte C
Producer: 20200217
In:
Advanced materials (Deerfield Beach, Fla.) vol. 31
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12.
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Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance. [electronic resource] by
- Brooun, Alexei
- Gajiwala, Ketan S
- Deng, Ya-Li
- Liu, Wei
- Bolaños, Ben
- Bingham, Patrick
- He, You-Ai
- Diehl, Wade
- Grable, Nicole
- Kung, Pei-Pei
- Sutton, Scott
- Maegley, Karen A
- Yu, Xiu
- Stewart, Al E
Producer: 20180727
In:
Nature communications vol. 7
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13.
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Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer. [electronic resource] by
- Cui, J Jean
- McTigue, Michele
- Nambu, Mitchell
- Tran-Dubé, Michelle
- Pairish, Mason
- Shen, Hong
- Jia, Lei
- Cheng, Hengmiao
- Hoffman, Jacqui
- Le, Phuong
- Jalaie, Mehran
- Goetz, Gilles H
- Ryan, Kevin
- Grodsky, Neil
- Deng, Ya-li
- Parker, Max
- Timofeevski, Sergei
- Murray, Brion W
- Yamazaki, Shinji
- Aguirre, Shirley
- Li, Qiuhua
- Zou, Helen
- Christensen, James
Producer: 20121204
In:
Journal of medicinal chemistry vol. 55
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14.
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PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations. [electronic resource] by
- Zou, Helen Y
- Li, Qiuhua
- Engstrom, Lars D
- West, Melissa
- Appleman, Vicky
- Wong, Katy A
- McTigue, Michele
- Deng, Ya-Li
- Liu, Wei
- Brooun, Alexei
- Timofeevski, Sergei
- McDonnell, Scott R P
- Jiang, Ping
- Falk, Matthew D
- Lappin, Patrick B
- Affolter, Timothy
- Nichols, Tim
- Hu, Wenyue
- Lam, Justine
- Johnson, Ted W
- Smeal, Tod
- Charest, Al
- Fantin, Valeria R
Producer: 20150604
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 112
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15.
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Acquired resistance to crizotinib from a mutation in CD74-ROS1. [electronic resource] by
- Awad, Mark M
- Katayama, Ryohei
- McTigue, Michele
- Liu, Wei
- Deng, Ya-Li
- Brooun, Alexei
- Friboulet, Luc
- Huang, Donghui
- Falk, Matthew D
- Timofeevski, Sergei
- Wilner, Keith D
- Lockerman, Elizabeth L
- Khan, Tahsin M
- Mahmood, Sidra
- Gainor, Justin F
- Digumarthy, Subba R
- Stone, James R
- Mino-Kenudson, Mari
- Christensen, James G
- Iafrate, A John
- Engelman, Jeffrey A
- Shaw, Alice T
Producer: 20130628
In:
The New England journal of medicine vol. 368
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16.
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Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F. [electronic resource] by
- Shaw, Alice T
- Friboulet, Luc
- Leshchiner, Ignaty
- Gainor, Justin F
- Bergqvist, Simon
- Brooun, Alexei
- Burke, Benjamin J
- Deng, Ya-Li
- Liu, Wei
- Dardaei, Leila
- Frias, Rosa L
- Schultz, Kate R
- Logan, Jennifer
- James, Leonard P
- Smeal, Tod
- Timofeevski, Sergei
- Katayama, Ryohei
- Iafrate, A John
- Le, Long
- McTigue, Michele
- Getz, Gad
- Johnson, Ted W
- Engelman, Jeffrey A
Producer: 20160119
In:
The New England journal of medicine vol. 374
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17.
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Discovery of pyrroloaminopyrazoles as novel PAK inhibitors. [electronic resource] by
- Guo, Chuangxing
- McAlpine, Indrawan
- Zhang, Junhu
- Knighton, Daniel D
- Kephart, Susan
- Johnson, M Catherine
- Li, Haitao
- Bouzida, Djamal
- Yang, Anle
- Dong, Liming
- Marakovits, Joseph
- Tikhe, Jayashree
- Richardson, Paul
- Guo, Lisa C
- Kania, Robert
- Edwards, Martin P
- Kraynov, Eugenia
- Christensen, James
- Piraino, Joseph
- Lee, Joseph
- Dagostino, Eleanor
- Del-Carmen, Christine
- Deng, Ya-Li
- Smeal, Tod
- Murray, Brion W
Producer: 20120907
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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18.
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Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations. [electronic resource] by
- Johnson, Ted W
- Richardson, Paul F
- Bailey, Simon
- Brooun, Alexei
- Burke, Benjamin J
- Collins, Michael R
- Cui, J Jean
- Deal, Judith G
- Deng, Ya-Li
- Dinh, Dac
- Engstrom, Lars D
- He, Mingying
- Hoffman, Jacqui
- Hoffman, Robert L
- Huang, Qinhua
- Kania, Robert S
- Kath, John C
- Lam, Hieu
- Lam, Justine L
- Le, Phuong T
- Lingardo, Laura
- Liu, Wei
- McTigue, Michele
- Palmer, Cynthia L
- Sach, Neal W
- Smeal, Tod
- Smith, Graham L
- Stewart, Albert E
- Timofeevski, Sergei
- Zhu, Huichun
- Zhu, Jinjiang
- Zou, Helen Y
- Edwards, Martin P
Producer: 20140820
In:
Journal of medicinal chemistry vol. 57
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19.
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Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497). [electronic resource] by
- Kung, Pei-Pei
- Bingham, Patrick
- Brooun, Alexei
- Collins, Michael
- Deng, Ya-Li
- Dinh, Dac
- Fan, Connie
- Gajiwala, Ketan S
- Grantner, Rita
- Gukasyan, Hovhannes J
- Hu, Wenyue
- Huang, Buwen
- Kania, Robert
- Kephart, Susan E
- Krivacic, Cody
- Kumpf, Robert A
- Khamphavong, Penney
- Kraus, Manfred
- Liu, Wei
- Maegley, Karen A
- Nguyen, Lisa
- Ren, Shijian
- Richter, Dan
- Rollins, Robert A
- Sach, Neal
- Sharma, Shikhar
- Sherrill, John
- Spangler, Jillian
- Stewart, Albert E
- Sutton, Scott
- Uryu, Sean
- Verhelle, Dominique
- Wang, Hui
- Wang, Shuiwang
- Wythes, Martin
- Xin, Shuibo
- Yamazaki, Shinji
- Zhu, Huichun
- Zhu, JinJiang
- Zehnder, Luke
- Edwards, Martin
Producer: 20190225
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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20.
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Design of potent and selective inhibitors to overcome clinical anaplastic lymphoma kinase mutations resistant to crizotinib. [electronic resource] by
- Huang, Qinhua
- Johnson, Ted W
- Bailey, Simon
- Brooun, Alexei
- Bunker, Kevin D
- Burke, Benjamin J
- Collins, Michael R
- Cook, Andrew S
- Cui, J Jean
- Dack, Kevin N
- Deal, Judith G
- Deng, Ya-Li
- Dinh, Dac
- Engstrom, Lars D
- He, Mingying
- Hoffman, Jacqui
- Hoffman, Robert L
- Johnson, Patrick S
- Kania, Robert S
- Lam, Hieu
- Lam, Justine L
- Le, Phuong T
- Li, Qiuhua
- Lingardo, Laura
- Liu, Wei
- Lu, Melissa West
- McTigue, Michele
- Palmer, Cynthia L
- Richardson, Paul F
- Sach, Neal W
- Shen, Hong
- Smeal, Tod
- Smith, Graham L
- Stewart, Albert E
- Timofeevski, Sergei
- Tsaparikos, Konstantinos
- Wang, Hui
- Zhu, Huichun
- Zhu, Jinjiang
- Zou, Helen Y
- Edwards, Martin P
Producer: 20140429
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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