Acquired resistance to crizotinib from a mutation in CD74-ROS1. [electronic resource]
Producer: 20130628Description: 2395-401 p. digitalISSN:- 1533-4406
- Adenocarcinoma -- drug therapy
- Crizotinib
- Drug Resistance -- genetics
- Fatal Outcome
- Female
- Humans
- Lung Neoplasms -- drug therapy
- Middle Aged
- Mutation
- Protein Conformation
- Protein Kinase Inhibitors -- therapeutic use
- Protein-Tyrosine Kinases -- chemistry
- Proto-Oncogene Proteins -- chemistry
- Pyrazoles -- therapeutic use
- Pyridines -- therapeutic use
- Structure-Activity Relationship
- Translocation, Genetic
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Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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