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Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells. [electronic resource] by
- Jin, Rihua
- Nakada, Mitsutoshi
- Teng, Lei
- Furuta, Takuya
- Sabit, Hemragul
- Hayashi, Yutaka
- Demuth, Tim
- Hirao, Atsushi
- Sato, Hiroshi
- Zhao, Gang
- Hamada, Jun-Ichiro
Producer: 20130618
In:
Neuroscience letters vol. 534
Availability: No items available.
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11.
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MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts. [electronic resource] by
- Rajeshkumar, N V
- De Oliveira, Elizabeth
- Ottenhof, Niki
- Watters, James
- Brooks, David
- Demuth, Tim
- Shumway, Stuart D
- Mizuarai, Shinji
- Hirai, Hiroshi
- Maitra, Anirban
- Hidalgo, Manuel
Producer: 20110915
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 17
Availability: No items available.
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12.
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MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival. [electronic resource] by
- Demuth, Tim
- Reavie, Linsey B
- Rennert, Jessica L
- Nakada, Mitsutoshi
- Nakada, Satoko
- Hoelzinger, Dominique B
- Beaudry, Christian E
- Henrichs, Amanda N
- Anderson, Eric M
- Berens, Michael E
Producer: 20070612
In:
Molecular cancer therapeutics vol. 6
Availability: No items available.
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13.
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Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. [electronic resource] by
- Cook, Natalie
- Frese, Kristopher K
- Bapiro, Tashinga E
- Jacobetz, Michael A
- Gopinathan, Aarthi
- Miller, Jodi L
- Rao, Sudhir S
- Demuth, Tim
- Howat, William J
- Jodrell, Duncan I
- Tuveson, David A
Producer: 20120508
In:
The Journal of experimental medicine vol. 209
Availability: No items available.
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14.
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RNAi screening of the kinome with cytarabine in leukemias. [electronic resource] by
- Tibes, Raoul
- Bogenberger, James M
- Chaudhuri, Leena
- Hagelstrom, R Tanner
- Chow, Donald
- Buechel, Megan E
- Gonzales, Irma M
- Demuth, Tim
- Slack, James
- Mesa, Ruben A
- Braggio, Esteban
- Yin, Hongwei H
- Arora, Shilpi
- Azorsa, David O
Producer: 20120507
In:
Blood vol. 119
Availability: No items available.
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15.
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Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study. [electronic resource] by
- Fouladi, Maryam
- Stewart, Clinton F
- Olson, James
- Wagner, Lars M
- Onar-Thomas, Arzu
- Kocak, Mehmet
- Packer, Roger J
- Goldman, Stewart
- Gururangan, Sridharan
- Gajjar, Amar
- Demuth, Tim
- Kun, Larry E
- Boyett, James M
- Gilbertson, Richard J
Producer: 20111102
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 29
Availability: No items available.
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16.
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A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy. [electronic resource] by
- Finazzi, Guido
- Vannucchi, Alessandro M
- Martinelli, Vincenzo
- Ruggeri, Marco
- Nobile, Francesco
- Specchia, Giorgina
- Pogliani, Enrico Maria
- Olimpieri, Odoardo Maria
- Fioritoni, Giuseppe
- Musolino, Caterina
- Cilloni, Daniela
- Sivera, Piera
- Barosi, Giovanni
- Finazzi, Maria Chiara
- Tollo, Silvia Di
- Demuth, Tim
- Barbui, Tiziano
- Rambaldi, Alessandro
Producer: 20130708
In:
British journal of haematology vol. 161
Availability: No items available.
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17.
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De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model. [electronic resource] by
- Watters, James W
- Cheng, Chun
- Majumder, Pradip K
- Wang, Ruojie
- Yalavarthi, Sireesha
- Meeske, Carol
- Kong, Lingxin
- Sun, Wenping
- Lin, Jie
- Heyer, Joerg
- Ware, Chris
- Winter, Christopher
- Reilly, John F
- Demuth, Tim
- Clark, Steve
- Chiu, M Isabel
- Robinson, Murray O
- Kohl, Nancy
- Kannan, Karuppiah
Producer: 20091221
In:
Cancer research vol. 69
Availability: No items available.
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18.
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Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors. [electronic resource] by
- Leijen, Suzanne
- van Geel, Robin M J M
- Pavlick, Anna C
- Tibes, Raoul
- Rosen, Lee
- Razak, Albiruni R Abdul
- Lam, Raymond
- Demuth, Tim
- Rose, Shelonitda
- Lee, Mark A
- Freshwater, Tomoko
- Shumway, Stuart
- Liang, Li Wen
- Oza, Amit M
- Schellens, Jan H M
- Shapiro, Geoffrey I
Producer: 20170807
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 34
Availability: No items available.
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19.
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Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines. [electronic resource] by
- Demuth, Tim
- Rennert, Jessica L
- Hoelzinger, Dominique B
- Reavie, Linsey B
- Nakada, Mitsutoshi
- Beaudry, Christian
- Nakada, Satoko
- Anderson, Eric M
- Henrichs, Amanda N
- McDonough, Wendy S
- Holz, David
- Joy, Anna
- Lin, Richard
- Pan, Kuang H
- Lih, Chih J
- Cohen, Stan N
- Berens, Michael E
Producer: 20080506
In:
BMC genomics vol. 9
Availability: No items available.
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20.
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Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors. [electronic resource] by
- Krop, Ian
- Demuth, Tim
- Guthrie, Tina
- Wen, Patrick Y
- Mason, Warren P
- Chinnaiyan, Prakash
- Butowski, Nicholas
- Groves, Morris D
- Kesari, Santosh
- Freedman, Steven J
- Blackman, Samuel
- Watters, James
- Loboda, Andrey
- Podtelezhnikov, Alexei
- Lunceford, Jared
- Chen, Cong
- Giannotti, Maxine
- Hing, Jeremy
- Beckman, Robert
- Lorusso, Patricia
Producer: 20121112
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 30
Availability: No items available.
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