Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. [electronic resource]
Producer: 20120511Description: 2405-14 p. digitalISSN:- 1538-8514
- Animals
- Brain Neoplasms -- drug therapy
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Glioblastoma -- drug therapy
- Humans
- Mice
- Mice, Nude
- Molecular Targeted Therapy
- Nuclear Proteins -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacokinetics
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Pyrazoles -- pharmacokinetics
- Pyrimidines -- pharmacokinetics
- Pyrimidinones
- Radiation Tolerance -- drug effects
- Radiation-Sensitizing Agents -- pharmacokinetics
- Up-Regulation -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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