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Dose Optimization for Anticancer Drug Combinations: Maximizing Therapeutic Index via Clinical Exposure-Toxicity/Preclinical Exposure-Efficacy Modeling. [electronic resource] by
- Bottino, Dean C
- Patel, Mayankbhai
- Kadakia, Ekta
- Zhou, Jilai
- Patel, Chirag
- Neuwirth, Rachel
- Iartchouk, Natasha
- Brake, Rachael
- Venkatakrishnan, Karthik
- Chakravarty, Arijit
Producer: 20200910
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 25
Availability: No items available.
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13.
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Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines. [electronic resource] by
- Driscoll, Denise L
- Chakravarty, Arijit
- Bowman, Doug
- Shinde, Vaishali
- Lasky, Kerri
- Shi, Judy
- Vos, Tricia
- Stringer, Bradley
- Amidon, Ben
- D'Amore, Natalie
- Hyer, Marc L
Producer: 20150810
In:
PloS one vol. 9
Availability: No items available.
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14.
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Preclinical pharmacokinetic/pharmacodynamic/efficacy relationships for alisertib, an investigational small-molecule inhibitor of Aurora A kinase. [electronic resource] by
- Palani, Santhosh
- Patel, Mayankbhai
- Huck, Jessica
- Zhang, Mengkun
- Balani, Suresh K
- Yang, Johnny
- Chen, Susan
- Mettetal, Jerome
- Manfredi, Mark
- Shyu, Wen Chyi
- Ecsedy, Jeffrey A
- Chakravarty, Arijit
Producer: 20140130
In:
Cancer chemotherapy and pharmacology vol. 72
Availability: No items available.
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15.
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Association Between Serum Prealbumin Level and Outcomes in Prevalent Kidney Transplant Recipients. [electronic resource] by
- Gaipov, Abduzhappar
- Jackson, Christopher D
- Talwar, Manish
- Balaraman, Vasanthi
- Chakravarty, Arijit
- Cseprekal, Orsolya
- Mathe, Zoltan
- Remport, Adam
- Kovesdy, Csaba P
- Eason, James D
- Mucsi, Istvan
- Molnar, Miklos Z
Producer: 20200716
In:
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation vol. 29
Availability: No items available.
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16.
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Preclinical drug metabolism and pharmacokinetics, and prediction of human pharmacokinetics and efficacious dose of the investigational Aurora A kinase inhibitor alisertib (MLN8237). [electronic resource] by
- Yang, Johnny J
- Li, Yu
- Chakravarty, Arijit
- Lu, Chuang
- Xia, Cindy Q
- Chen, Susan
- Pusalkar, Sandeep
- Zhang, Mengkun
- Ecsedy, Jeffrey
- Manfredi, Mark G
- Wu, Jing-Tao
- Shyu, Wen Chyi
- Balani, Suresh K
Producer: 20150112
In:
Drug metabolism letters vol. 7
Availability: No items available.
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17.
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Translational exposure-efficacy modeling to optimize the dose and schedule of taxanes combined with the investigational Aurora A kinase inhibitor MLN8237 (alisertib). [electronic resource] by
- Huck, Jessica J
- Zhang, Mengkun
- Mettetal, Jerome
- Chakravarty, Arijit
- Venkatakrishnan, Karthik
- Zhou, Xiaofei
- Kleinfield, Rob
- Hyer, Marc L
- Kannan, Karuppiah
- Shinde, Vaishali
- Dorner, Andy
- Manfredi, Mark G
- Shyu, Wen Chyi
- Ecsedy, Jeffrey A
Producer: 20151117
In:
Molecular cancer therapeutics vol. 13
Availability: No items available.
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18.
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Phase I study of the selective Aurora A kinase inhibitor MLN8054 in patients with advanced solid tumors: safety, pharmacokinetics, and pharmacodynamics. [electronic resource] by
- Macarulla, Teresa
- Cervantes, Andres
- Elez, Elena
- Rodríguez-Braun, Edith
- Baselga, José
- Roselló, Susana
- Sala, Gemma
- Blasco, Inma
- Danaee, Hadi
- Lee, Yih
- Ecsedy, Jeffrey
- Shinde, Vaishali
- Chakravarty, Arijit
- Bowman, Douglas
- Liu, Hua
- Eton, Omar
- Fingert, Howard
- Tabernero, Josep
Producer: 20110310
In:
Molecular cancer therapeutics vol. 9
Availability: No items available.
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19.
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Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays. [electronic resource] by
- Manfredi, Mark G
- Ecsedy, Jeffrey A
- Chakravarty, Arijit
- Silverman, Lee
- Zhang, Mengkun
- Hoar, Kara M
- Stroud, Stephen G
- Chen, Wei
- Shinde, Vaishali
- Huck, Jessica J
- Wysong, Deborah R
- Janowick, David A
- Hyer, Marc L
- Leroy, Patrick J
- Gershman, Rachel E
- Silva, Matthew D
- Germanos, Melissa S
- Bolen, Joseph B
- Claiborne, Christopher F
- Sells, Todd B
Producer: 20120611
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 17
Availability: No items available.
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20.
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Preclinical pharmacokinetic/pharmacodynamic modeling and simulation in the pharmaceutical industry: an IQ consortium survey examining the current landscape. [electronic resource] by
- Schuck, Edgar
- Bohnert, Tonika
- Chakravarty, Arijit
- Damian-Iordache, Valeriu
- Gibson, Christopher
- Hsu, Cheng-Pang
- Heimbach, Tycho
- Krishnatry, Anu Shilpa
- Liederer, Bianca M
- Lin, Jing
- Maurer, Tristan
- Mettetal, Jerome T
- Mudra, Daniel R
- Nijsen, Marjoleen Jma
- Raybon, Joseph
- Schroeder, Patricia
- Schuck, Virna
- Suryawanshi, Satyendra
- Su, Yaming
- Trapa, Patrick
- Tsai, Alice
- Vakilynejad, Majid
- Wang, Shining
- Wong, Harvey
Producer: 20150715
In:
The AAPS journal vol. 17
Availability: No items available.
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