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On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models. [electronic resource] by
- Cho, Hyejin
- Du, Xinlin
- Rizzi, James P
- Liberzon, Ella
- Chakraborty, Abhishek A
- Gao, Wenhua
- Carvo, Ingrid
- Signoretti, Sabina
- Bruick, Richard K
- Josey, John A
- Wallace, Eli M
- Kaelin, William G
Producer: 20170314
In:
Nature vol. 539
Availability: No items available.
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9.
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. [electronic resource] by
- Guo, Jianping
- Chakraborty, Abhishek A
- Liu, Pengda
- Gan, Wenjian
- Zheng, Xingnan
- Inuzuka, Hiroyuki
- Wang, Bin
- Zhang, Jinfang
- Zhang, Linli
- Yuan, Min
- Novak, Jesse
- Cheng, Jin Q
- Toker, Alex
- Signoretti, Sabina
- Zhang, Qing
- Asara, John M
- Kaelin, William G
- Wei, Wenyi
Producer: 20170223
In:
Science (New York, N.Y.) vol. 353
Availability: No items available.
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10.
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HIF activation causes synthetic lethality between the [electronic resource] by
- Chakraborty, Abhishek A
- Nakamura, Eijiro
- Qi, Jun
- Creech, Amanda
- Jaffe, Jacob D
- Paulk, Joshiawa
- Novak, Jesse S
- Nagulapalli, Kshithija
- McBrayer, Samuel K
- Cowley, Glenn S
- Pineda, Javier
- Song, Jiaxi
- Wang, Yaoyu E
- Carr, Steven A
- Root, David E
- Signoretti, Sabina
- Bradner, James E
- Kaelin, William G
Producer: 20180330
In:
Science translational medicine vol. 9
Availability: No items available.
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11.
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EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection. [electronic resource] by
- Olenchock, Benjamin A
- Moslehi, Javid
- Baik, Alan H
- Davidson, Shawn M
- Williams, Jeremy
- Gibson, William J
- Chakraborty, Abhishek A
- Pierce, Kerry A
- Miller, Christine M
- Hanse, Eric A
- Kelekar, Ameeta
- Sullivan, Lucas B
- Wagers, Amy J
- Clish, Clary B
- Vander Heiden, Matthew G
- Kaelin, William G
Producer: 20160726
In:
Cell vol. 164
Availability: No items available.
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12.
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EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection. [electronic resource] by
- Olenchock, Benjamin A
- Moslehi, Javid
- Baik, Alan H
- Davidson, Shawn M
- Williams, Jeremy
- Gibson, William J
- Chakraborty, Abhishek A
- Pierce, Kerry A
- Miller, Christine M
- Hanse, Eric A
- Kelekar, Ameeta
- Sullivan, Lucas B
- Wagers, Amy J
- Clish, Clary B
- Vander Heiden, Matthew G
- Kaelin, William G
Producer: 20160811
In:
Cell vol. 165
Availability: No items available.
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13.
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Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. [electronic resource] by
- Chakraborty, Abhishek A
- Laukka, Tuomas
- Myllykoski, Matti
- Ringel, Alison E
- Booker, Matthew A
- Tolstorukov, Michael Y
- Meng, Yuzhong Jeff
- Meier, Samuel R
- Jennings, Rebecca B
- Creech, Amanda L
- Herbert, Zachary T
- McBrayer, Samuel K
- Olenchock, Benjamin A
- Jaffe, Jacob D
- Haigis, Marcia C
- Beroukhim, Rameen
- Signoretti, Sabina
- Koivunen, Peppi
- Kaelin, William G
Producer: 20190812
In:
Science (New York, N.Y.) vol. 363
Availability: No items available.
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14.
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The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis. [electronic resource] by
- Oser, Matthew G
- Sabet, Amin H
- Gao, Wenhua
- Chakraborty, Abhishek A
- Schinzel, Anna C
- Jennings, Rebecca B
- Fonseca, Raquel
- Bonal, Dennis M
- Booker, Matthew A
- Flaifel, Abdallah
- Novak, Jesse S
- Christensen, Camilla L
- Zhang, Hua
- Herbert, Zachary T
- Tolstorukov, Michael Y
- Buss, Elizabeth J
- Wong, Kwok-Kin
- Bronson, Roderick T
- Nguyen, Quang-De
- Signoretti, Sabina
- Kaelin, William G
Producer: 20191220
In:
Genes & development vol. 33
Availability: No items available.
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15.
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Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. [electronic resource] by
- Zheng, Xingnan
- Zhai, Bo
- Koivunen, Peppi
- Shin, Sandra J
- Lu, Gang
- Liu, Jiayun
- Geisen, Christoph
- Chakraborty, Abhishek A
- Moslehi, Javid J
- Smalley, David M
- Wei, Xin
- Chen, Xian
- Chen, Zhengming
- Beres, Justine M
- Zhang, Jing
- Tsao, Jen Lan
- Brenner, Mitchell C
- Zhang, Yuqing
- Fan, Cheng
- DePinho, Ronald A
- Paik, Jihye
- Gygi, Steven P
- Kaelin, William G
- Zhang, Qing
Producer: 20140902
In:
Genes & development vol. 28
Availability: No items available.
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16.
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Cells Lacking the [electronic resource] by
- Oser, Matthew G
- Fonseca, Raquel
- Chakraborty, Abhishek A
- Brough, Rachel
- Spektor, Alexander
- Jennings, Rebecca B
- Flaifel, Abdallah
- Novak, Jesse S
- Gulati, Aditi
- Buss, Elizabeth
- Younger, Scott T
- McBrayer, Samuel K
- Cowley, Glenn S
- Bonal, Dennis M
- Nguyen, Quang-De
- Brulle-Soumare, Laura
- Taylor, Paula
- Cairo, Stefano
- Ryan, Colm J
- Pease, Elizabeth J
- Maratea, Kim
- Travers, Jon
- Root, David E
- Signoretti, Sabina
- Pellman, David
- Ashton, Susan
- Lord, Christopher J
- Barry, Simon T
- Kaelin, William G
Producer: 20200326
In:
Cancer discovery vol. 9
Availability: No items available.
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17.
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Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. [electronic resource] by
- McBrayer, Samuel K
- Mayers, Jared R
- DiNatale, Gabriel J
- Shi, Diana D
- Khanal, Januka
- Chakraborty, Abhishek A
- Sarosiek, Kristopher A
- Briggs, Kimberly J
- Robbins, Alissa K
- Sewastianik, Tomasz
- Shareef, Sarah J
- Olenchock, Benjamin A
- Parker, Seth J
- Tateishi, Kensuke
- Spinelli, Jessica B
- Islam, Mirazul
- Haigis, Marcia C
- Looper, Ryan E
- Ligon, Keith L
- Bernstein, Bradley E
- Carrasco, Ruben D
- Cahill, Daniel P
- Asara, John M
- Metallo, Christian M
- Yennawar, Neela H
- Vander Heiden, Matthew G
- Kaelin, William G
Producer: 20190617
In:
Cell vol. 175
Availability: No items available.
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