In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis. [electronic resource]
Producer: 20131024Description: 524-30 p. digitalISSN:- 1557-7430
- Amino Acid Substitution
- Computational Biology
- Genetic Predisposition to Disease
- Gonadal Dysgenesis, 46,XY -- genetics
- Gonadal Dysgenesis, Mixed -- genetics
- HEK293 Cells
- Hedgehog Proteins -- genetics
- Humans
- Molecular Dynamics Simulation
- Mutagenesis, Site-Directed
- Point Mutation
- Protein Stability
- Protein Structure, Secondary
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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