In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis.

Castro, Josué Joram

In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis. [electronic resource] - DNA and cell biology Sep 2013 - 524-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1557-7430

10.1089/dna.2013.2052 doi


Amino Acid Substitution
Computational Biology
Genetic Predisposition to Disease
Gonadal Dysgenesis, 46,XY--genetics
Gonadal Dysgenesis, Mixed--genetics
HEK293 Cells
Hedgehog Proteins--genetics
Humans
Molecular Dynamics Simulation
Mutagenesis, Site-Directed
Point Mutation
Protein Stability
Protein Structure, Secondary