Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure. [electronic resource]
Producer: 20040601Description: 31-51 p. digitalISSN:- 0167-6806
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- drug effects
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- drug effects
- Adenocarcinoma -- drug therapy
- Antineoplastic Agents -- pharmacology
- Breast Neoplasms -- drug therapy
- Caspase 9
- Caspases -- drug effects
- Cell Line, Tumor
- Doxorubicin -- pharmacology
- Drug Interactions -- physiology
- Drug Resistance, Neoplasm -- physiology
- Humans
- Neoplasm Proteins -- drug effects
- Paclitaxel -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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