Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure.
Guo, Baoqing
Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure. [electronic resource] - Breast cancer research and treatment May 2004 - 31-51 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0167-6806
10.1023/B:BREA.0000021046.29834.12 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--drug effects
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--drug effects
Adenocarcinoma--drug therapy
Antineoplastic Agents--pharmacology
Breast Neoplasms--drug therapy
Caspase 9
Caspases--drug effects
Cell Line, Tumor
Doxorubicin--pharmacology
Drug Interactions--physiology
Drug Resistance, Neoplasm--physiology
Humans
Neoplasm Proteins--drug effects
Paclitaxel--pharmacology
Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure. [electronic resource] - Breast cancer research and treatment May 2004 - 31-51 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0167-6806
10.1023/B:BREA.0000021046.29834.12 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--drug effects
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--drug effects
Adenocarcinoma--drug therapy
Antineoplastic Agents--pharmacology
Breast Neoplasms--drug therapy
Caspase 9
Caspases--drug effects
Cell Line, Tumor
Doxorubicin--pharmacology
Drug Interactions--physiology
Drug Resistance, Neoplasm--physiology
Humans
Neoplasm Proteins--drug effects
Paclitaxel--pharmacology