Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion. [electronic resource]
Producer: 20051101Description: 5705-20 p. digitalISSN:- 0022-2623
- Administration, Oral
- Alzheimer Disease -- blood
- Amyloid beta-Peptides -- antagonists & inhibitors
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Blood-Brain Barrier -- metabolism
- Caco-2 Cells
- Cell Line, Tumor
- Cell Membrane Permeability
- Cyclooxygenase Inhibitors -- pharmacology
- Flurbiprofen -- analogs & derivatives
- Glioma
- Humans
- Immunoassay
- In Vitro Techniques
- Injections, Intravenous
- Mice
- Mice, Transgenic
- Peptide Fragments -- antagonists & inhibitors
- Rats
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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