Co-expression of recombinant human CYP2C9 with human cytochrome P450 reductase in protease deficient S. cerevisiae strain at a higher scale yields an enzyme of higher specific activity. [electronic resource]
Producer: 20110404Description: 246-53 p. digitalISSN:- 1874-0758
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Cytochrome P-450 CYP2C9
- Cytochromes b5 -- genetics
- Fluorescein -- metabolism
- Humans
- Kinetics
- Microsomes -- enzymology
- NADPH-Ferrihemoprotein Reductase -- biosynthesis
- Peptide Hydrolases -- deficiency
- Recombinant Proteins -- metabolism
- Saccharomyces cerevisiae -- enzymology
- Substrate Specificity
- Sulfaphenazole -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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