Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression. [electronic resource]
Producer: 20160815Description: 273-90 p. digitalISSN:- 1540-9538
- Animals
- Disease Progression
- Hedgehog Proteins -- metabolism
- Hematopoiesis
- Hematopoietic Stem Cells -- metabolism
- Humans
- Janus Kinase 2 -- genetics
- Leukemia -- etiology
- Ligands
- Lymphopenia -- etiology
- Mice
- Mice, Knockout
- Mice, Transgenic
- Mutant Proteins -- genetics
- Myeloproliferative Disorders -- etiology
- Osteoblasts -- metabolism
- Patched Receptors
- Patched-2 Receptor
- Phenotype
- Polycythemia Vera -- genetics
- Receptors, Cell Surface -- deficiency
- Recombinant Proteins -- genetics
- Signal Transduction
- Stem Cell Niche
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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