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401.
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Phase I clinical and pharmacokinetic study of kahalalide F in patients with advanced androgen refractory prostate cancer. [electronic resource] by
- Rademaker-Lakhai, Jeany M
- Horenblas, Simon
- Meinhardt, Willem
- Stokvis, Ellen
- de Reijke, Theo M
- Jimeno, José M
- Lopez-Lazaro, Luis
- Lopez Martin, José A
- Beijnen, Jos H
- Schellens, Jan H M
Producer: 20050620
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 11
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402.
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update. [electronic resource] by
- Amstutz, Ursula
- Henricks, Linda M
- Offer, Steven M
- Barbarino, Julia
- Schellens, Jan H M
- Swen, Jesse J
- Klein, Teri E
- McLeod, Howard L
- Caudle, Kelly E
- Diasio, Robert B
- Schwab, Matthias
Producer: 20190409
In:
Clinical pharmacology and therapeutics vol. 103
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403.
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Circulating epithelial tumor cell analysis in CSF in patients with leptomeningeal metastases. [electronic resource] by
- van Bussel, Mark T J
- Pluim, Dick
- Milojkovic Kerklaan, Bojana
- Bol, Mijke
- Sikorska, Karolina
- Linders, Dorothé T C
- van den Broek, Daan
- Beijnen, Jos H
- Schellens, Jan H M
- Brandsma, Dieta
Producer: 20200518
In:
Neurology vol. 94
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404.
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Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir. [electronic resource] by
- Yu, Huixin
- Janssen, Julie M
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- Nuijen, Bastiaan
- Stuurman, Rik E
- Marchetti, Serena
- Schellens, Jan H M
- Beijnen, Jos H
- Dorlo, Thomas P C
- Huitema, Alwin D R
Producer: 20210902
In:
Investigational new drugs vol. 38
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405.
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Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors. [electronic resource] by
- Siegel-Lakhai, Wandena S
- Beijnen, Jos H
- Vervenne, Walter L
- Boot, Henk
- Keessen, Marianne
- Versola, Melissa
- Koch, Kevin M
- Smith, Deborah A
- Pandite, Lini
- Richel, Dirk J
- Schellens, Jan H M
Producer: 20071026
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 13
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406.
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Capecitabine-based treatment of a patient with a novel DPYD genotype and complete dihydropyrimidine dehydrogenase deficiency. [electronic resource] by
- Henricks, Linda M
- Siemerink, Ester J M
- Rosing, Hilde
- Meijer, Judith
- Goorden, Susan M I
- Polstra, Abeltje M
- Zoetekouw, Lida
- Cats, Annemieke
- Schellens, Jan H M
- van Kuilenburg, André B P
Producer: 20171214
In:
International journal of cancer vol. 142
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407.
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Development and clinical validation of an LC-MS/MS method for the quantification of pazopanib in DBS. [electronic resource] by
- Verheijen, Remy B
- Bins, Sander
- Thijssen, Bas
- Rosing, Hilde
- Nan, Lianda
- Schellens, Jan H M
- Mathijssen, Ron H J
- Lolkema, Martijn P
- Beijnen, Jos H
- Steeghs, Neeltje
- Huitema, Alwin D R
Producer: 20160919
In:
Bioanalysis vol. 8
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408.
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Clinical and pharmacologic study of the novel prodrug delimotecan (MEN 4901/T-0128) in patients with solid tumors. [electronic resource] by
- Veltkamp, Stephan A
- Witteveen, Els O
- Capriati, Angela
- Crea, Attilio
- Animati, Fabio
- Voogel-Fuchs, Marja
- van den Heuvel, Ingeborg J G M
- Beijnen, Jos H
- Voest, Emile E
- Schellens, Jan H M
Producer: 20090105
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 14
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409.
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Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer. [electronic resource] by
- Gast, Marie-Christine W
- Zapatka, Marc
- van Tinteren, Harm
- Bontenbal, Marijke
- Span, Paul N
- Tjan-Heijnen, Vivianne C G
- Knol, Jaco C
- Jimenez, Connie R
- Schellens, Jan H M
- Beijnen, Jos H
Producer: 20111215
In:
Journal of cancer research and clinical oncology vol. 137
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410.
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Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines. [electronic resource] by
- Meulendijks, Didier
- Henricks, Linda M
- van Kuilenburg, André B P
- Jacobs, Bart A W
- Aliev, Abidin
- Rozeman, Lisette
- Meijer, Judith
- Beijnen, Jos H
- de Graaf, Hiltje
- Cats, Annemieke
- Schellens, Jan H M
Producer: 20170606
In:
Cancer chemotherapy and pharmacology vol. 78
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411.
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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours. [electronic resource] by
- de Jonge, Maja
- de Weger, Vincent A
- Dickson, Mark A
- Langenberg, Marlies
- Le Cesne, Axel
- Wagner, Andrew J
- Hsu, Karl
- Zheng, Wei
- Macé, Sandrine
- Tuffal, Gilles
- Thomas, Koruth
- Schellens, Jan H M
Producer: 20170807
In:
European journal of cancer (Oxford, England : 1990) vol. 76
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412.
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Phase I evaluation of telatinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in combination with irinotecan and capecitabine in patients with advanced solid tumors. [electronic resource] by
- Langenberg, Marlies H G
- Witteveen, Petronella O
- Roodhart, Jeanine M
- Verheul, Henk M W
- Mergui-Roelvink, Marja
- van der Sar, Jana
- Brendel, Erich
- Laferriere, Nicole
- Schellens, Jan H M
- Voest, Emile E
Producer: 20100806
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 16
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413.
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Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines. [electronic resource] by
- Brandon, Esther F A
- Bosch, Tessa M
- Deenen, Maarten J
- Levink, Rianne
- van der Wal, Everdina
- van Meerveld, Joyce B M
- Bijl, Monique
- Beijnen, Jos H
- Schellens, Jan H M
- Meijerman, Irma
Producer: 20060404
In:
Toxicology and applied pharmacology vol. 211
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414.
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415.
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Individualized Pazopanib Dosing: A Prospective Feasibility Study in Cancer Patients. [electronic resource] by
- Verheijen, Remy B
- Bins, Sander
- Mathijssen, Ron H J
- Lolkema, Martijn P
- van Doorn, Leni
- Schellens, Jan H M
- Beijnen, Jos H
- Langenberg, Marlies H G
- Huitema, Alwin D R
- Steeghs, Neeltje
Producer: 20180116
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
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416.
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Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose. [electronic resource] by
- de Vries Schultink, Aurelia H M
- Doornbos, Robert P
- Bakker, Alexander B H
- Bol, Kees
- Throsby, Mark
- Geuijen, Cecile
- Maussang, David
- Schellens, Jan H M
- Beijnen, Jos H
- Huitema, Alwin D R
Producer: 20190610
In:
Investigational new drugs vol. 36
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417.
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418.
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419.
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Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers. [electronic resource] by
- Lunenburg, Carin A T C
- Henricks, Linda M
- Dreussi, Eva
- Peters, Femke P
- Fiocco, Marta
- Meulendijks, Didier
- Toffoli, Giuseppe
- Guchelaar, Henk-Jan
- Swen, Jesse J
- Cecchin, Erika
- Schellens, Jan H M
- Gelderblom, Hans
Producer: 20191002
In:
European journal of cancer (Oxford, England : 1990) vol. 104
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420.
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