Results
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41.
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Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors. [electronic resource] by
- Bokhovchuk, Fedir
- Mesrouze, Yannick
- Delaunay, Clara
- Martin, Typhaine
- Villard, Frédéric
- Meyerhofer, Marco
- Fontana, Patrizia
- Zimmermann, Catherine
- Erdmann, Dirk
- Furet, Pascal
- Scheufler, Clemens
- Schmelzle, Tobias
- Chène, Patrick
Producer: 20201221
In:
Protein science : a publication of the Protein Society vol. 29
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42.
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Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument. [electronic resource] by
- Furet, Pascal
- Masuya, Keiichi
- Kallen, Joerg
- Stachyra-Valat, Thérèse
- Ruetz, Stephan
- Guagnano, Vito
- Holzer, Philipp
- Mah, Robert
- Stutz, Stefan
- Vaupel, Andrea
- Chène, Patrick
- Jeay, Sébastien
- Schlapbach, Achim
Producer: 20170717
In:
Bioorganic & medicinal chemistry letters vol. 26
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43.
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NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. [electronic resource] by
- Jensen, Michael Rugaard
- Schoepfer, Joseph
- Radimerski, Thomas
- Massey, Andrew
- Guy, Chantale T
- Brueggen, Josef
- Quadt, Cornelia
- Buckler, Alan
- Cozens, Robert
- Drysdale, Martin J
- Garcia-Echeverria, Carlos
- Chène, Patrick
Producer: 20080721
In:
Breast cancer research : BCR vol. 10
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44.
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Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800. [electronic resource] by
- Massey, Andrew J
- Schoepfer, Joseph
- Brough, Paul A
- Brueggen, Josef
- Chène, Patrick
- Drysdale, Martin J
- Pfaar, Ulrike
- Radimerski, Thomas
- Ruetz, Stephan
- Schweitzer, Alain
- Wood, Mike
- Garcia-Echeverria, Carlos
- Jensen, Michael Rugaard
Producer: 20100707
In:
Molecular cancer therapeutics vol. 9
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45.
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Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. [electronic resource] by
- Holzer, Philipp
- Masuya, Keiichi
- Furet, Pascal
- Kallen, Joerg
- Valat-Stachyra, Therese
- Ferretti, Stéphane
- Berghausen, Joerg
- Bouisset-Leonard, Michèle
- Buschmann, Nicole
- Pissot-Soldermann, Carole
- Rynn, Caroline
- Ruetz, Stephan
- Stutz, Stefan
- Chène, Patrick
- Jeay, Sébastien
- Gessier, Francois
Producer: 20151116
In:
Journal of medicinal chemistry vol. 58
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46.
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Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. [electronic resource] by
- Kallen, Joerg
- Izaac, Aude
- Chau, Suzanne
- Wirth, Emmanuelle
- Schoepfer, Joseph
- Mah, Robert
- Schlapbach, Achim
- Stutz, Stefan
- Vaupel, Andrea
- Guagnano, Vito
- Masuya, Keiichi
- Stachyra, Therese-Marie
- Salem, Bahaa
- Chene, Patrick
- Gessier, Francois
- Holzer, Philipp
- Furet, Pascal
Producer: 20200706
In:
ChemMedChem vol. 14
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47.
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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. [electronic resource] by
- Maira, Sauveur-Michel
- Stauffer, Frédéric
- Brueggen, Josef
- Furet, Pascal
- Schnell, Christian
- Fritsch, Christine
- Brachmann, Saskia
- Chène, Patrick
- De Pover, Alain
- Schoemaker, Kevin
- Fabbro, Doriano
- Gabriel, Daniela
- Simonen, Marjo
- Murphy, Leon
- Finan, Peter
- Sellers, William
- García-Echeverría, Carlos
Producer: 20080908
In:
Molecular cancer therapeutics vol. 7
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48.
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2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors. [electronic resource] by
- Gerspacher, Marc
- Furet, Pascal
- Pissot-Soldermann, Carole
- Gaul, Christoph
- Holzer, Philipp
- Vangrevelinghe, Eric
- Lang, Marc
- Erdmann, Dirk
- Radimerski, Thomas
- Regnier, Catherine H
- Chene, Patrick
- De Pover, Alain
- Hofmann, Francesco
- Baffert, Fabienne
- Buhl, Thomas
- Aichholz, Reiner
- Blasco, Francesca
- Endres, Ralf
- Trappe, Jörg
- Drueckes, Peter
Producer: 20100527
In:
Bioorganic & medicinal chemistry letters vol. 20
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49.
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Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805. [electronic resource] by
- Baffert, Fabienne
- Régnier, Catherine H
- De Pover, Alain
- Pissot-Soldermann, Carole
- Tavares, Gisele A
- Blasco, Francesca
- Brueggen, Josef
- Chène, Patrick
- Drueckes, Peter
- Erdmann, Dirk
- Furet, Pascal
- Gerspacher, Marc
- Lang, Marc
- Ledieu, David
- Nolan, Lynda
- Ruetz, Stephan
- Trappe, Joerg
- Vangrevelinghe, Eric
- Wartmann, Markus
- Wyder, Lorenza
- Hofmann, Francesco
- Radimerski, Thomas
Producer: 20101104
In:
Molecular cancer therapeutics vol. 9
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50.
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Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor. [electronic resource] by
- Maira, Sauveur-Michel
- Pecchi, Sabina
- Huang, Alan
- Burger, Matthew
- Knapp, Mark
- Sterker, Dario
- Schnell, Christian
- Guthy, Daniel
- Nagel, Tobi
- Wiesmann, Marion
- Brachmann, Saskia
- Fritsch, Christine
- Dorsch, Marion
- Chène, Patrick
- Shoemaker, Kevin
- De Pover, Alain
- Menezes, Daniel
- Martiny-Baron, Georg
- Fabbro, Doriano
- Wilson, Christopher J
- Schlegel, Robert
- Hofmann, Francesco
- García-Echeverría, Carlos
- Sellers, William R
- Voliva, Charles F
Producer: 20120618
In:
Molecular cancer therapeutics vol. 11
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51.
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Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials. [electronic resource] by
- Fritsch, Christine
- Huang, Alan
- Chatenay-Rivauday, Christian
- Schnell, Christian
- Reddy, Anupama
- Liu, Manway
- Kauffmann, Audrey
- Guthy, Daniel
- Erdmann, Dirk
- De Pover, Alain
- Furet, Pascal
- Gao, Hui
- Ferretti, Stephane
- Wang, Youzhen
- Trappe, Joerg
- Brachmann, Saskia M
- Maira, Sauveur-Michel
- Wilson, Christopher
- Boehm, Markus
- Garcia-Echeverria, Carlos
- Chene, Patrick
- Wiesmann, Marion
- Cozens, Robert
- Lehar, Joseph
- Schlegel, Robert
- Caravatti, Giorgio
- Hofmann, Francesco
- Sellers, William R
Producer: 20150102
In:
Molecular cancer therapeutics vol. 13
Availability: No items available.
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52.
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"4D Biology for health and disease" workshop report. [electronic resource] by
- Abrahams, Jan-Pieter
- Apweiler, Rolf
- Balling, Rudi
- Bertero, Michela G
- Bujnicki, Janusz M
- Chayen, Naomi E
- Chène, Patrick
- Corthals, Gary L
- Dyląg, Tomasz
- Förster, Friedrich
- Heck, Albert J R
- Henderson, Peter J F
- Herwig, Ralf
- Jehenson, Philippe
- Kokalj, Sasa Jenko
- Laue, Ernest
- Legrain, Pierre
- Martens, Lennart
- Migliorini, Cristiano
- Musacchio, Andrea
- Podobnik, Marjetka
- Schertler, Gebhard F X
- Schreiber, Gideon
- Sixma, Titia K
- Smit, August B
- Stuart, David
- Svergun, Dmitri I
- Taussig, Michael J
Producer: 20120315
In:
New biotechnology vol. 28
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53.
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Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone. [electronic resource] by
- Brough, Paul A
- Barril, Xavier
- Borgognoni, Jenifer
- Chene, Patrick
- Davies, Nicholas G M
- Davis, Ben
- Drysdale, Martin J
- Dymock, Brian
- Eccles, Suzanne A
- Garcia-Echeverria, Carlos
- Fromont, Christophe
- Hayes, Angela
- Hubbard, Roderick E
- Jordan, Allan M
- Jensen, Michael Rugaard
- Massey, Andrew
- Merrett, Angela
- Padfield, Antony
- Parsons, Rachel
- Radimerski, Thomas
- Raynaud, Florence I
- Robertson, Alan
- Roughley, Stephen D
- Schoepfer, Joseph
- Simmonite, Heather
- Sharp, Swee Y
- Surgenor, Allan
- Valenti, Melanie
- Walls, Steven
- Webb, Paul
- Wood, Mike
- Workman, Paul
- Wright, Lisa
Producer: 20090921
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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54.
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Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization. [electronic resource] by
- Karpov, Alexei S
- Nieto-Oberhuber, Cristina M
- Abrams, Tinya
- Beng-Louka, Edwige
- Blanco, Enrique
- Chamoin, Sylvie
- Chene, Patrick
- Dacquignies, Isabelle
- Daniel, Dylan
- Dillon, Michael P
- Doumampouom-Metoul, Lionel
- Drosos, Nikolaos
- Fedoseev, Pavel
- Furegati, Markus
- Granda, Brian
- Grotzfeld, Robert M
- Hess Clark, Suzanna
- Joly, Emilie
- Jones, Darryl
- Lacaud-Baumlin, Marion
- Lagasse-Guerro, Stephanie
- Lorenzana, Edward G
- Mallet, William
- Martyniuk, Piotr
- Marzinzik, Andreas L
- Mesrouze, Yannick
- Nocito, Sandro
- Oei, Yoko
- Perruccio, Francesca
- Piizzi, Grazia
- Richard, Etienne
- Rudewicz, Patrick J
- Schindler, Patrick
- Velay, Mélanie
- Venstrom, Kristine
- Wang, Peiyin
- Zurini, Mauro
- Lafrance, Marc
Publication details: ACS medicinal chemistry letters Dec 2019
In:
ACS medicinal chemistry letters vol. 10
Availability: No items available.
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