Results
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21.
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A designed ankyrin repeat protein evolved to picomolar affinity to Her2. [electronic resource] by
- Zahnd, Christian
- Wyler, Emanuel
- Schwenk, Jochen M
- Steiner, Daniel
- Lawrence, Michael C
- McKern, Neil M
- Pecorari, Frédéric
- Ward, Colin W
- Joos, Thomas O
- Plückthun, Andreas
Producer: 20070806
In:
Journal of molecular biology vol. 369
Availability: No items available.
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22.
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An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. [electronic resource] by
- Burgess, Antony W
- Cho, Hyun-Soo
- Eigenbrot, Charles
- Ferguson, Kathryn M
- Garrett, Thomas P J
- Leahy, Daniel J
- Lemmon, Mark A
- Sliwkowski, Mark X
- Ward, Colin W
- Yokoyama, Shigeyuki
Producer: 20031106
In:
Molecular cell vol. 12
Availability: No items available.
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23.
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The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. [electronic resource] by
- Lou, Meizhen
- Garrett, Thomas P J
- McKern, Neil M
- Hoyne, Peter A
- Epa, V Chandana
- Bentley, John D
- Lovrecz, George O
- Cosgrove, Leah J
- Frenkel, Maurice J
- Ward, Colin W
Producer: 20061107
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 103
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24.
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The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. [electronic resource] by
- Garrett, Thomas P J
- McKern, Neil M
- Lou, Meizhen
- Elleman, Thomas C
- Adams, Timothy E
- Lovrecz, George O
- Kofler, Michael
- Jorissen, Robert N
- Nice, Edouard C
- Burgess, Antony W
- Ward, Colin W
Producer: 20030402
In:
Molecular cell vol. 11
Availability: No items available.
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25.
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A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation. [electronic resource] by
- Koziolek, Eva J
- Donoghue, Jacqueline F
- Bentley, John D
- Lovrecz, George
- Dolezal, Olan
- Ward, Colin W
- Rothacker, Julie
- Nice, Edouard C
- Burgess, Antony W
- Hafner, M
- Johns, Terrance G
- Adams, Timothy E
Producer: 20130404
In:
Growth factors (Chur, Switzerland) vol. 30
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26.
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Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change. [electronic resource] by
- Whitten, Andrew E
- Smith, Brian J
- Menting, John G
- Margetts, Mai B
- McKern, Neil M
- Lovrecz, George O
- Adams, Timothy E
- Richards, Kim
- Bentley, John D
- Trewhella, Jill
- Ward, Colin W
- Lawrence, Michael C
Producer: 20091221
In:
Journal of molecular biology vol. 394
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27.
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Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists. [electronic resource] by
- Smith, Brian J
- Huang, Kun
- Kong, Geoffrey
- Chan, Shu Jin
- Nakagawa, Satoe
- Menting, John G
- Hu, Shi-Quan
- Whittaker, Jonathan
- Steiner, Donald F
- Katsoyannis, Panayotis G
- Ward, Colin W
- Weiss, Michael A
- Lawrence, Michael C
Producer: 20100514
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
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28.
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A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activity in vivo. [electronic resource] by
- Adams, Timothy E
- Koziolek, Eva J
- Hoyne, Peter H
- Bentley, John D
- Lu, Louis
- Lovrecz, George
- Ward, Colin W
- Lee, F T
- Scott, Andrew M
- Nash, Andrew D
- Rothacker, Julie
- Nice, Edouard C
- Burgess, Antony W
- Johns, Terrance G
Producer: 20090729
In:
Growth factors (Chur, Switzerland) vol. 27
Availability: No items available.
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29.
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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. [electronic resource] by
- Garrett, Thomas P J
- McKern, Neil M
- Lou, Meizhen
- Elleman, Thomas C
- Adams, Timothy E
- Lovrecz, George O
- Zhu, Hong-Jian
- Walker, Francesca
- Frenkel, Morry J
- Hoyne, Peter A
- Jorissen, Robert N
- Nice, Edouard C
- Burgess, Antony W
- Ward, Colin W
Producer: 20021023
In:
Cell vol. 110
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30.
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How insulin engages its primary binding site on the insulin receptor. [electronic resource] by
- Menting, John G
- Whittaker, Jonathan
- Margetts, Mai B
- Whittaker, Linda J
- Kong, Geoffrey K-W
- Smith, Brian J
- Watson, Christopher J
- Záková, Lenka
- Kletvíková, Emília
- Jiráček, Jiří
- Chan, Shu Jin
- Steiner, Donald F
- Dodson, Guy G
- Brzozowski, Andrzej M
- Weiss, Michael A
- Ward, Colin W
- Lawrence, Michael C
Producer: 20130226
In:
Nature vol. 493
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31.
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Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor. [electronic resource] by
- Johns, Terrance G
- Adams, Timothy E
- Cochran, Jennifer R
- Hall, Nathan E
- Hoyne, Peter A
- Olsen, Mark J
- Kim, Yong-Sung
- Rothacker, Julie
- Nice, Edouard C
- Walker, Francesca
- Ritter, Gerd
- Jungbluth, Achim A
- Old, Lloyd J
- Ward, Colin W
- Burgess, Antony W
- Wittrup, K Dane
- Scott, Andrew M
Producer: 20040817
In:
The Journal of biological chemistry vol. 279
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32.
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Protective hinge in insulin opens to enable its receptor engagement. [electronic resource] by
- Menting, John G
- Yang, Yanwu
- Chan, Shu Jin
- Phillips, Nelson B
- Smith, Brian J
- Whittaker, Jonathan
- Wickramasinghe, Nalinda P
- Whittaker, Linda J
- Pandyarajan, Vijay
- Wan, Zhu-li
- Yadav, Satya P
- Carroll, Julie M
- Strokes, Natalie
- Roberts, Charles T
- Ismail-Beigi, Faramarz
- Milewski, Wieslawa
- Steiner, Donald F
- Chauhan, Virander S
- Ward, Colin W
- Weiss, Michael A
- Lawrence, Michael C
Producer: 20141103
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 111
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33.
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Structure of the insulin receptor ectodomain reveals a folded-over conformation. [electronic resource] by
- McKern, Neil M
- Lawrence, Michael C
- Streltsov, Victor A
- Lou, Mei-Zhen
- Adams, Timothy E
- Lovrecz, George O
- Elleman, Thomas C
- Richards, Kim M
- Bentley, John D
- Pilling, Patricia A
- Hoyne, Peter A
- Cartledge, Kellie A
- Pham, Tam M
- Lewis, Jennifer L
- Sankovich, Sonia E
- Stoichevska, Violet
- Da Silva, Elizabeth
- Robinson, Christine P
- Frenkel, Maurice J
- Sparrow, Lindsay G
- Fernley, Ross T
- Epa, V Chandana
- Ward, Colin W
Producer: 20061013
In:
Nature vol. 443
Availability: No items available.
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