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An intermediate pH unfolding transition abrogates the ability of IgE to interact with its high affinity receptor FcepsilonRIalpha. [electronic resource] by
- Demarest, Stephen J
- Hopp, Jennifer
- Chung, Julie
- Hathaway, Karen
- Mertsching, Elisabeth
- Cao, Xianjun
- George, Judy
- Miatkowski, Konrad
- LaBarre, Michael J
- Shields, Michael
- Kehry, Marilyn R
Producer: 20061127
In:
The Journal of biological chemistry vol. 281
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Neutralization of Clostridium difficile toxin A using antibody combinations. [electronic resource] by
- Demarest, Stephen J
- Hariharan, Mangala
- Elia, Marikka
- Salbato, Jared
- Jin, Ping
- Bird, Colin
- Short, Jay M
- Kimmel, Bruce E
- Dudley, Michael
- Woodnutt, Gary
- Hansen, Geneviève
Producer: 20110729
In:
mAbs vol. 2
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Protein design of IgG/TCR chimeras for the co-expression of Fab-like moieties within bispecific antibodies. [electronic resource] by
- Wu, Xiufeng
- Sereno, Arlene J
- Huang, Flora
- Zhang, Kai
- Batt, Micheal
- Fitchett, Jonathan R
- He, Dongmei
- Rick, Heather L
- Conner, Elaine M
- Demarest, Stephen J
Producer: 20151130
In:
mAbs vol. 7
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Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression. [electronic resource] by
- Demarest, Stephen J
- Chen, Gang
- Kimmel, Bruce E
- Gustafson, David
- Wu, Jane
- Salbato, Jared
- Poland, John
- Elia, Marikka
- Tan, Xuqiu
- Wong, Ken
- Short, Jay
- Hansen, Geneviève
Producer: 20060905
In:
Protein engineering, design & selection : PEDS vol. 19
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Stability engineering of scFvs for the development of bispecific and multivalent antibodies. [electronic resource] by
- Miller, Brian R
- Demarest, Stephen J
- Lugovskoy, Alexey
- Huang, Flora
- Wu, Xiufeng
- Snyder, William B
- Croner, Lisa J
- Wang, Norman
- Amatucci, Aldo
- Michaelson, Jennifer S
- Glaser, Scott M
Producer: 20101214
In:
Protein engineering, design & selection : PEDS vol. 23
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Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules. [electronic resource] by
- Jordan, Jacob L
- Arndt, Joseph W
- Hanf, Karl
- Li, Guohui
- Hall, Janine
- Demarest, Stephen
- Huang, Flora
- Wu, Xiufeng
- Miller, Brian
- Glaser, Scott
- Fernandez, Erik J
- Wang, Deping
- Lugovskoy, Alexey
Producer: 20100202
In:
Proteins vol. 77
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Combination of two insulin-like growth factor-I receptor inhibitory antibodies targeting distinct epitopes leads to an enhanced antitumor response. [electronic resource] by
- Dong, Jianying
- Demarest, Stephen J
- Sereno, Arlene
- Tamraz, Susan
- Langley, Emma
- Doern, Adam
- Snipas, Tracey
- Perron, Keli
- Joseph, Ingrid
- Glaser, Scott M
- Ho, Steffan N
- Reff, Mitchell E
- Hariharan, Kandasamy
Producer: 20110217
In:
Molecular cancer therapeutics vol. 9
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Computationally Designed Bispecific Antibodies using Negative State Repertoires. [electronic resource] by
- Leaver-Fay, Andrew
- Froning, Karen J
- Atwell, Shane
- Aldaz, Hector
- Pustilnik, Anna
- Lu, Frances
- Huang, Flora
- Yuan, Richard
- Hassanali, Saleema
- Chamberlain, Aaron K
- Fitchett, Jonathan R
- Demarest, Stephen J
- Kuhlman, Brian
Producer: 20161216
In:
Structure (London, England : 1993) vol. 24
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Fab-based bispecific antibody formats with robust biophysical properties and biological activity. [electronic resource] by
- Wu, Xiufeng
- Sereno, Arlene J
- Huang, Flora
- Lewis, Steven M
- Lieu, Ricky L
- Weldon, Caroline
- Torres, Carina
- Fine, Cody
- Batt, Micheal A
- Fitchett, Jonathan R
- Glasebrook, Andrew L
- Kuhlman, Brian
- Demarest, Stephen J
Producer: 20160322
In:
mAbs vol. 7
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Evaluation of Tyro3 expression, Gas6-mediated Akt phosphorylation, and the impact of anti-Tyro3 antibodies in melanoma cell lines. [electronic resource] by
- Demarest, Stephen J
- Gardner, Jennifer
- Vendel, Michelle C
- Ailor, Eric
- Szak, Suzanne
- Huang, Flora
- Doern, Adam
- Tan, Xiangyang
- Yang, Weixing
- Grueneberg, Dorre A
- Richards, Edward J
- Endege, Wilson O
- Harlow, Ed
- Koopman, Louise A
Producer: 20130705
In:
Biochemistry vol. 52
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Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR. [electronic resource] by
- Michaelson, Jennifer S
- Demarest, Stephen J
- Miller, Brian
- Amatucci, Aldo
- Snyder, William B
- Wu, Xiufeng
- Huang, Flora
- Phan, Samantha
- Gao, Sharon
- Doern, Adam
- Farrington, Graham K
- Lugovskoy, Alexey
- Joseph, Ingrid
- Bailly, Veronique
- Wang, Xin
- Garber, Ellen
- Browning, Jeff
- Glaser, Scott M
Producer: 20100325
In:
mAbs vol. 1
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Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. [electronic resource] by
- Lewis, Steven M
- Wu, Xiufeng
- Pustilnik, Anna
- Sereno, Arlene
- Huang, Flora
- Rick, Heather L
- Guntas, Gurkan
- Leaver-Fay, Andrew
- Smith, Eric M
- Ho, Carolyn
- Hansen-Estruch, Christophe
- Chamberlain, Aaron K
- Truhlar, Stephanie M
- Conner, Elaine M
- Atwell, Shane
- Kuhlman, Brian
- Demarest, Stephen J
Producer: 20140922
In:
Nature biotechnology vol. 32
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Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity. [electronic resource] by
- Dong, Jianying
- Sereno, Arlene
- Snyder, William B
- Miller, Brian R
- Tamraz, Susan
- Doern, Adam
- Favis, Michael
- Wu, Xiufeng
- Tran, Hon
- Langley, Emma
- Joseph, Ingrid
- Boccia, Antonio
- Kelly, Rebecca
- Wortham, Kathleen
- Wang, Qin
- Berquist, Lisa
- Huang, Flora
- Gao, Sharon X
- Zhang, Ying
- Lugovskoy, Alexey
- Martin, Shelly
- Gouvis, Heather
- Berkowitz, Steven
- Chiang, Gisela
- Reff, Mitchell
- Glaser, Scott M
- Hariharan, Kandasamy
- Demarest, Stephen J
Producer: 20110324
In:
The Journal of biological chemistry vol. 286
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A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity. [electronic resource] by
- Dong, Jianying
- Sereno, Arlene
- Aivazian, Dikran
- Langley, Emma
- Miller, Brian R
- Snyder, William B
- Chan, Eric
- Cantele, Matt
- Morena, Ronald
- Joseph, Ingrid B J K
- Boccia, Antonio
- Virata, Cyrus
- Gamez, James
- Yco, Grace
- Favis, Michael
- Wu, Xiufeng
- Graff, Christilyn P
- Wang, Qin
- Rohde, Ellen
- Rennard, Rachel
- Berquist, Lisa
- Huang, Flora
- Zhang, Ying
- Gao, Sharon X
- Ho, Steffan N
- Demarest, Stephen J
- Reff, Mitchell E
- Hariharan, Kandasamy
- Glaser, Scott M
Producer: 20111227
In:
mAbs vol. 3
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Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo. [electronic resource] by
- Doern, Adam
- Cao, Xianjun
- Sereno, Arlene
- Reyes, Christopher L
- Altshuler, Angelina
- Huang, Flora
- Hession, Cathy
- Flavier, Albert
- Favis, Michael
- Tran, Hon
- Ailor, Eric
- Levesque, Melissa
- Murphy, Tracey
- Berquist, Lisa
- Tamraz, Susan
- Snipas, Tracey
- Garber, Ellen
- Shestowsky, William S
- Rennard, Rachel
- Graff, Christilyn P
- Wu, Xiufeng
- Snyder, William
- Cole, Lindsay
- Gregson, David
- Shields, Michael
- Ho, Steffan N
- Reff, Mitchell E
- Glaser, Scott M
- Dong, Jianying
- Demarest, Stephen J
- Hariharan, Kandasamy
Producer: 20090520
In:
The Journal of biological chemistry vol. 284
Availability: No items available.
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