Results
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21.
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6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents. [electronic resource] by
- Naus, Petr
- Pohl, Radek
- Votruba, Ivan
- Dzubák, Petr
- Hajdúch, Marián
- Ameral, Ria
- Birkus, Gabriel
- Wang, Ting
- Ray, Adrian S
- Mackman, Richard
- Cihlar, Tomas
- Hocek, Michal
Producer: 20100202
In:
Journal of medicinal chemistry vol. 53
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22.
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Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat. [electronic resource] by
- Lepist, Eve-Irene
- Zhang, Xuexiang
- Hao, Jia
- Huang, Jane
- Kosaka, Alan
- Birkus, Gabriel
- Murray, Bernard P
- Bannister, Roy
- Cihlar, Tomas
- Huang, Yong
- Ray, Adrian S
Producer: 20150511
In:
Kidney international vol. 86
Availability: No items available.
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23.
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Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors. [electronic resource] by
- Xing, Weimei
- Barauskas, Ona
- Kirschberg, Thorsten
- Niedziela-Majka, Anita
- Clarke, Michael
- Birkus, Gabriel
- Weissburg, Perry
- Liu, Xiaohong
- Schultz, Brian E
- Sakowicz, Roman
- Kwon, HyockJoo
- Feng, Joy Y
Producer: 20171011
In:
PloS one vol. 12
Availability: No items available.
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24.
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Anti-HBV activity of retinoid drugs in vitro versus in vivo. [electronic resource] by
- Birkus, Gabriel
- Snyder, Chelsea
- Jordan, Robert
- Kobayashi, Tetsuya
- Dick, Ryan
- Puscau, Vlad
- Li, Li
- Ramirez, Ricardo
- Willkom, Madeleine
- Morikawa, Yoshida
- Delaney Iv, William E
- Schmitz, Uli
Producer: 20200707
In:
Antiviral research vol. 169
Availability: No items available.
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25.
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GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions. [electronic resource] by
- Wolfgang, Grushenka H I
- Shibata, Riri
- Wang, Jianying
- Ray, Adrian S
- Wu, Sylvia
- Doerrfler, Edward
- Reiser, Hans
- Lee, William A
- Birkus, Gabriel
- Christensen, Neil D
- Andrei, Graciela
- Snoeck, Robert
Producer: 20090928
In:
Antimicrobial agents and chemotherapy vol. 53
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26.
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Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment. [electronic resource] by
- Feng, Joy Y
- Wang, Ting
- Park, Yeojin
- Babusis, Darius
- Birkus, Gabriel
- Xu, Yili
- Voitenleitner, Christian
- Fenaux, Martijn
- Yang, Huiling
- Eng, Stacey
- Tirunagari, Neeraj
- Kirschberg, Thorsten
- Cho, Aesop
- Ray, Adrian S
Producer: 20190923
In:
Antimicrobial agents and chemotherapy vol. 62
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27.
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Metabolism and pharmacokinetics of the anti-hepatitis C virus nucleotide prodrug GS-6620. [electronic resource] by
- Murakami, Eisuke
- Wang, Ting
- Babusis, Darius
- Lepist, Eve-Irene
- Sauer, Dorothea
- Park, Yeojin
- Vela, Jennifer E
- Shih, Robert
- Birkus, Gabriel
- Stefanidis, Dimitrios
- Kim, Choung U
- Cho, Aesop
- Ray, Adrian S
Producer: 20141112
In:
Antimicrobial agents and chemotherapy vol. 58
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28.
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Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases. [electronic resource] by
- Clarke, Michael O
- Mackman, Richard
- Byun, Daniel
- Hui, Hon
- Barauskas, Ona
- Birkus, Gabriel
- Chun, Byoung-Kwon
- Doerffler, Edward
- Feng, Joy
- Karki, Kapil
- Lee, Gary
- Perron, Michel
- Siegel, Dustin
- Swaminathan, Swami
- Lee, William
Producer: 20160223
In:
Bioorganic & medicinal chemistry letters vol. 25
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29.
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Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines. [electronic resource] by
- Bourderioux, Aurelie
- Naus, Petr
- Perlíková, Pavla
- Pohl, Radek
- Pichová, Iva
- Votruba, Ivan
- Dzubák, Petr
- Konecný, Petr
- Hajdúch, Marián
- Stray, Kirsten M
- Wang, Ting
- Ray, Adrian S
- Feng, Joy Y
- Birkus, Gabriel
- Cihlar, Tomas
- Hocek, Michal
Producer: 20111007
In:
Journal of medicinal chemistry vol. 54
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30.
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Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. [electronic resource] by
- Mejdrová, Ivana
- Chalupská, Dominika
- Kögler, Martin
- Šála, Michal
- Plačková, Pavla
- Baumlová, Adriana
- Hřebabecký, Hubert
- Procházková, Eliška
- Dejmek, Milan
- Guillon, Rémi
- Strunin, Dmytro
- Weber, Jan
- Lee, Gary
- Birkus, Gabriel
- Mertlíková-Kaiserová, Helena
- Boura, Evzen
- Nencka, Radim
Producer: 20150806
In:
Journal of medicinal chemistry vol. 58
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31.
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Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. [electronic resource] by
- Mejdrová, Ivana
- Chalupská, Dominika
- Plačková, Pavla
- Müller, Christin
- Šála, Michal
- Klíma, Martin
- Baumlová, Adriana
- Hřebabecký, Hubert
- Procházková, Eliška
- Dejmek, Milan
- Strunin, Dmytro
- Weber, Jan
- Lee, Gary
- Matoušová, Marika
- Mertlíková-Kaiserová, Helena
- Ziebuhr, John
- Birkus, Gabriel
- Boura, Evzen
- Nencka, Radim
Producer: 20170807
In:
Journal of medicinal chemistry vol. 60
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32.
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Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. [electronic resource] by
- Novotná, Barbora
- Vaneková, Lenka
- Zavřel, Martin
- Buděšínský, Miloš
- Dejmek, Milan
- Smola, Miroslav
- Gutten, Ondrej
- Tehrani, Zahra Aliakbar
- Pimková Polidarová, Markéta
- Brázdová, Andrea
- Liboska, Radek
- Štěpánek, Ivan
- Vavřina, Zdeněk
- Jandušík, Tomáš
- Nencka, Radim
- Rulíšek, Lubomír
- Bouřa, Evžen
- Brynda, Jiří
- Páv, Ondřej
- Birkuš, Gabriel
Producer: 20200622
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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33.
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Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148. [electronic resource] by
- Mackman, Richard L
- Ray, Adrian S
- Hui, Hon C
- Zhang, Lijun
- Birkus, Gabriel
- Boojamra, Constantine G
- Desai, Manoj C
- Douglas, Janet L
- Gao, Ying
- Grant, Deborah
- Laflamme, Genevieve
- Lin, Kuei-Ying
- Markevitch, David Y
- Mishra, Ruchika
- McDermott, Martin
- Pakdaman, Rowchanak
- Petrakovsky, Oleg V
- Vela, Jennifer E
- Cihlar, Tomas
Producer: 20100827
In:
Bioorganic & medicinal chemistry vol. 18
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34.
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GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma. [electronic resource] by
- Reiser, Hans
- Wang, Jianying
- Chong, Lee
- Watkins, William J
- Ray, Adrian S
- Shibata, Riri
- Birkus, Gabriel
- Cihlar, Tomas
- Wu, Sylvia
- Li, Bei
- Liu, Xiaohong
- Henne, Ilana N
- Wolfgang, Grushenka H I
- Desai, Manoj
- Rhodes, Gerald R
- Fridland, Arnold
- Lee, William A
- Plunkett, William
- Vail, David
- Thamm, Douglas H
- Jeraj, Robert
- Tumas, Daniel B
Producer: 20080918
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 14
Availability: No items available.
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35.
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Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug. [electronic resource] by
- Feng, Joy Y
- Cheng, Guofeng
- Perry, Jason
- Barauskas, Ona
- Xu, Yili
- Fenaux, Martijn
- Eng, Stacey
- Tirunagari, Neeraj
- Peng, Betty
- Yu, Mei
- Tian, Yang
- Lee, Yu-Jen
- Stepan, George
- Lagpacan, Leanna L
- Jin, Debi
- Hung, Magdeleine
- Ku, Karin S
- Han, Bin
- Kitrinos, Kathryn
- Perron, Michel
- Birkus, Gabriel
- Wong, Kelly A
- Zhong, Weidong
- Kim, Choung U
- Carey, Anne
- Cho, Aesop
- Ray, Adrian S
Producer: 20141112
In:
Antimicrobial agents and chemotherapy vol. 58
Availability: No items available.
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36.
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Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. [electronic resource] by
- Kirschberg, Thorsten A
- Metobo, Sammy
- Clarke, Michael O
- Aktoudianakis, Vangelis
- Babusis, Darius
- Barauskas, Ona
- Birkus, Gabriel
- Butler, Thomas
- Byun, Daniel
- Chin, Gregory
- Doerffler, Edward
- Edwards, Thomas E
- Fenaux, Martijn
- Lee, Rick
- Lew, Willard
- Mish, Michael R
- Murakami, Eisuke
- Park, Yeojin
- Squires, Neil H
- Tirunagari, Neeraj
- Wang, Ting
- Whitcomb, Mark
- Xu, Jie
- Yang, Huiling
- Ye, Hong
- Zhang, Lijun
- Appleby, Todd C
- Feng, Joy Y
- Ray, Adrian S
- Cho, Aesop
- Kim, Choung U
Producer: 20170718
In:
Bioorganic & medicinal chemistry letters vol. 27
Availability: No items available.
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