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1521.
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MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. [electronic resource] by
- Hirai, Hiroshi
- Sootome, Hiroshi
- Nakatsuru, Yoko
- Miyama, Katsuyoshi
- Taguchi, Shunsuke
- Tsujioka, Kyoko
- Ueno, Yoko
- Hatch, Harold
- Majumder, Pradip K
- Pan, Bo-Sheng
- Kotani, Hidehito
Producer: 20101104
In:
Molecular cancer therapeutics vol. 9
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1522.
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In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption. [electronic resource] by
- Larbouret, Christel
- Gaborit, Nadège
- Chardès, Thierry
- Coelho, Mickaël
- Campigna, Emmanuelle
- Bascoul-Mollevi, Caroline
- Mach, Jean-Pierre
- Azria, David
- Robert, Bruno
- Pèlegrin, André
Producer: 20120419
In:
Neoplasia (New York, N.Y.) vol. 14
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1523.
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1524.
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Pathologic complete response after preoperative anti-HER2 therapy correlates with alterations in PTEN, FOXO, phosphorylated Stat5, and autophagy protein signaling. [electronic resource] by
- Holmes, Frankie Ann
- Espina, Virginia
- Liotta, Lance A
- Nagarwala, Yasir M
- Danso, Michael
- McIntyre, Kristi J
- Osborne, Cynthia R C
- Anderson, Thomas
- Krekow, Lea
- Blum, Joanne L
- Pippen, John
- Florance, Allison
- Mahoney, Janine
- O'Shaughnessy, Joyce A
Producer: 20140714
In:
BMC research notes vol. 6
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1525.
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Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients. [electronic resource] by
- Duchnowska, Renata
- Wysocki, Piotr J
- Korski, Konstanty
- Czartoryska-Arłukowicz, Bogumiła
- Niwińska, Anna
- Orlikowska, Marlena
- Radecka, Barbara
- Studziński, Maciej
- Demlova, Regina
- Ziółkowska, Barbara
- Merdalska, Monika
- Hajac, Łukasz
- Myśliwiec, Paulina
- Zuziak, Dorota
- Dębska-Szmich, Sylwia
- Lang, Istvan
- Foszczyńska-Kłoda, Małgorzata
- Karczmarek-Borowska, Bożenna
- Żawrocki, Anton
- Kowalczyk, Anna
- Biernat, Wojciech
- Jassem, Jacek
Producer: 20161107
In:
Oncotarget vol. 7
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1526.
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A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation. [electronic resource] by
- Thiessen, Brian
- Stewart, Clinton
- Tsao, Ming
- Kamel-Reid, Suzanne
- Schaiquevich, Paula
- Mason, Warren
- Easaw, Jacob
- Belanger, Karl
- Forsyth, Peter
- McIntosh, Lynn
- Eisenhauer, Elizabeth
Producer: 20110509
In:
Cancer chemotherapy and pharmacology vol. 65
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1527.
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Neutral 5-substituted 4-indazolylaminoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. [electronic resource] by
- Barlaam, Bernard
- Acton, David G
- Ballard, Peter
- Bradbury, Robert H
- Cross, Darren
- Ducray, Richard
- Germain, Hervé
- Hudson, Kevin
- Klinowska, Teresa
- Magnien, Françoise
- Ogilvie, Donald J
- Olivier, Annie
- Ross, Helen S
- Smith, Robin
- Trigwell, Cath B
- Vautier, Michel
- Wright, Lindsay
Producer: 20080609
In:
Bioorganic & medicinal chemistry letters vol. 18
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1528.
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Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells. [electronic resource] by
- Raina, D
- Uchida, Y
- Kharbanda, A
- Rajabi, H
- Panchamoorthy, G
- Jin, C
- Kharbanda, S
- Scaltriti, M
- Baselga, J
- Kufe, D
Producer: 20140828
In:
Oncogene vol. 33
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1529.
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Immunoglobulin G fragment C receptor polymorphisms and efficacy of preoperative chemotherapy plus trastuzumab and lapatinib in HER2-positive breast cancer. [electronic resource] by
- Musolino, A
- Naldi, N
- Dieci, M V
- Zanoni, D
- Rimanti, A
- Boggiani, D
- Sgargi, P
- Generali, D G
- Piacentini, F
- Ambroggi, M
- Cagossi, K
- Gianni, L
- Sarti, S
- Bisagni, G
- Ardizzoni, A
- Conte, P F
- Guarneri, V
Producer: 20170605
In:
The pharmacogenomics journal vol. 16
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1530.
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1531.
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Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes. [electronic resource] by
- Watson, Spencer S
- Dane, Mark
- Chin, Koei
- Tatarova, Zuzana
- Liu, Moqing
- Liby, Tiera
- Thompson, Wallace
- Smith, Rebecca
- Nederlof, Michel
- Bucher, Elmar
- Kilburn, David
- Whitman, Matthew
- Sudar, Damir
- Mills, Gordon B
- Heiser, Laura M
- Jonas, Oliver
- Gray, Joe W
- Korkola, James E
Producer: 20190930
In:
Cell systems vol. 6
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1532.
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The 41-gene classifier TRAR predicts response of HER2 positive breast cancer patients in the NeoALTTO study. [electronic resource] by
- Di Cosimo, Serena
- Triulzi, Tiziana
- Pizzamiglio, Sara
- De Cecco, Loris
- de Azambuja, Evandro
- Fumagalli, Debora
- Putzai, Lajos
- Harbeck, Nadia
- Izquierdo, Miguel
- Peña, Lorena de la
- Daidone, Maria Grazia
- Huober, Jens
- Gori, Stefania
- Cinieri, Saverio
- Torri, Valter
- Baselga, Jose
- Piccart, Martine
- de Braud, Filippo G
- Apolone, Giovanni
- Verderio, Paolo
- Tagliabue, Elda
Producer: 20200608
In:
European journal of cancer (Oxford, England : 1990) vol. 118
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1533.
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Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation. [electronic resource] by
- Yi, Yong
- Chen, Deshi
- Ao, Juan
- Zhang, Wenhua
- Yi, Jianqiao
- Ren, Xiaokun
- Fei, Junjie
- Li, Fengtian
- Niu, Mengmeng
- Chen, Hu
- Luo, Yangkun
- Luo, Zhijun
- Xiao, Zhi-Xiong Jim
Producer: 20200720
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 117
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1534.
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Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression. [electronic resource] by
- Nencioni, Alessio
- Cea, Michele
- Garuti, Anna
- Passalacqua, Mario
- Raffaghello, Lizzia
- Soncini, Debora
- Moran, Eva
- Zoppoli, Gabriele
- Pistoia, Vito
- Patrone, Franco
- Ballestrero, Alberto
Producer: 20100930
In:
PloS one vol. 5
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1535.
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1536.
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1537.
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1538.
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Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: American Society of Clinical Oncology clinical practice guideline. [electronic resource] by
- Giordano, Sharon H
- Temin, Sarah
- Kirshner, Jeffrey J
- Chandarlapaty, Sarat
- Crews, Jennie R
- Davidson, Nancy E
- Esteva, Francisco J
- Gonzalez-Angulo, Ana M
- Krop, Ian
- Levinson, Jennifer
- Lin, Nancy U
- Modi, Shanu
- Patt, Debra A
- Perez, Edith A
- Perlmutter, Jane
- Ramakrishna, Naren
- Winer, Eric P
Producer: 20140815
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 32
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1539.
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1540.
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