The synthesis and biological activity of a series of 2,4-diaminopyrido[2,3-d]pyrimidine based antifolates as antineoplastic and antiarthritic agents. [electronic resource]
Producer: 19990413Description: 75-8 p. digitalISSN:- 0960-894X
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- chemistry
- Antineoplastic Agents -- chemistry
- Arthritis, Experimental -- drug therapy
- Drug Evaluation, Preclinical
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemistry
- Folic Acid Antagonists -- chemical synthesis
- Glutamates -- chemistry
- Guanine -- analogs & derivatives
- Hydroxymethyl and Formyl Transferases -- antagonists & inhibitors
- Leukemia -- drug therapy
- Lymphoma, Non-Hodgkin -- drug therapy
- Mice
- Pemetrexed
- Peptide Synthases -- metabolism
- Phosphoribosylglycinamide Formyltransferase
- Pyrimidines -- chemistry
- Rats
- Structure-Activity Relationship
- Tetrahydrofolates -- chemistry
- Thymidylate Synthase -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.