IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2. [electronic resource]
Producer: 19990413Description: 2081-6 p. digitalISSN:- 0022-1767
- Adaptor Proteins, Signal Transducing
- Antigens, Differentiation
- Cells, Cultured
- Cytokines -- physiology
- GRB2 Adaptor Protein
- Humans
- Interleukin-2 -- physiology
- Interleukin-4 -- physiology
- Intracellular Signaling Peptides and Proteins
- Janus Kinase 3
- Killer Cells, Natural -- enzymology
- Macromolecular Substances
- Membrane Glycoproteins -- metabolism
- Molecular Weight
- Neural Cell Adhesion Molecule L1
- Neural Cell Adhesion Molecules -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoproteins -- biosynthesis
- Phosphorylation
- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatase, Non-Receptor Type 6
- Protein Tyrosine Phosphatases -- biosynthesis
- Protein-Tyrosine Kinases -- physiology
- Proteins -- metabolism
- Receptors, Immunologic
- SH2 Domain-Containing Protein Tyrosine Phosphatases
- Signal Transduction -- immunology
- Substrate Specificity -- immunology
- T-Lymphocytes -- enzymology
- src Homology Domains -- immunology
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Publication Type: Journal Article
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