Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes. [electronic resource]
Producer: 19990413Description: 1480-7 p. digitalISSN:- 0022-1767
- Animals
- Antigens, CD -- chemistry
- Binding Sites
- COS Cells
- Cytokine Receptor gp130
- Epitopes -- chemistry
- Humans
- Interleukin-11 -- chemistry
- Interleukin-11 Receptor alpha Subunit
- Interleukin-6 -- chemistry
- Macromolecular Substances
- Membrane Glycoproteins -- chemistry
- Models, Molecular
- Mutagenesis, Site-Directed
- Protein Conformation
- Receptors, Interleukin -- chemistry
- Receptors, Interleukin-11
- Receptors, Interleukin-6 -- chemistry
- Signal Transduction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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