Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.

Kurth, I

Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Feb 1999 - 1480-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-1767


Animals
Antigens, CD--chemistry
Binding Sites
COS Cells
Cytokine Receptor gp130
Epitopes--chemistry
Humans
Interleukin-11--chemistry
Interleukin-11 Receptor alpha Subunit
Interleukin-6--chemistry
Macromolecular Substances
Membrane Glycoproteins--chemistry
Models, Molecular
Mutagenesis, Site-Directed
Protein Conformation
Receptors, Interleukin--chemistry
Receptors, Interleukin-11
Receptors, Interleukin-6--chemistry
Signal Transduction