Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L. [electronic resource]
Producer: 19990204Description: 125-39 p. digitalISSN:- 0006-4971
- Adult
- Aged
- Aged, 80 and over
- Antigens, CD34 -- analysis
- Autocrine Communication -- genetics
- Cell Division -- genetics
- Cell Line
- Cell-Free System
- Cells, Cultured
- Child
- Female
- Humans
- Male
- Megakaryocytes -- pathology
- Middle Aged
- Mutation
- Neoplasm Proteins
- Primary Myelofibrosis -- blood
- Proto-Oncogene Proteins -- genetics
- Receptors, Cytokine
- Receptors, Thrombopoietin
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Thrombocythemia, Essential -- blood
- Thrombopoietin -- blood
- Transcription Factors -- metabolism
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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