d,l-buthionine-(S,R)-sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors. [electronic resource]
Producer: 19990216Description: 1961-8 p. digitalISSN:- 1078-0432
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Buthionine Sulfoximine -- administration & dosage
- Doxorubicin -- administration & dosage
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Drug Synergism
- Female
- Fibrosarcoma -- drug therapy
- Genes, MDR -- physiology
- Glutathione -- blood
- Humans
- Immunohistochemistry
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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