Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase. [electronic resource]
Producer: 19980911Description: 691-7 p. digitalISSN:- 0950-9232
- Adaptor Proteins, Signal Transducing
- Adaptor Proteins, Vesicular Transport
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases -- metabolism
- Enzyme Activation
- Epidermal Growth Factor -- pharmacology
- GRB2 Adaptor Protein
- Guanine Nucleotide Exchange Factors
- Mutation
- Nerve Growth Factors -- pharmacology
- PC12 Cells
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphatidylinositols -- metabolism
- Protein Binding
- Protein Serine-Threonine Kinases
- Proteins -- metabolism
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-akt
- Rats
- Receptor Protein-Tyrosine Kinases -- genetics
- Receptor, trkA
- Receptors, Nerve Growth Factor -- genetics
- Shc Signaling Adaptor Proteins
- Src Homology 2 Domain-Containing, Transforming Protein 1
- Tyrosine -- genetics
- ras Guanine Nucleotide Exchange Factors
- ras Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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