Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production. [electronic resource]
Producer: 19980910Description: 5166-77 p. digitalISSN:- 0270-7306
- CD4-Positive T-Lymphocytes -- cytology
- Cell Cycle
- Cell Line
- Cell Transformation, Viral
- Clone Cells
- Cytokines -- biosynthesis
- DNA Methylation
- DNA Modification Methylases -- biosynthesis
- Gene Expression Regulation, Enzymologic
- HIV Core Protein p24 -- biosynthesis
- HIV-1 -- immunology
- Humans
- Interferon-gamma -- biosynthesis
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- T-Lymphocytes -- cytology
- T-Lymphocytes, Helper-Inducer -- immunology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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