2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. [electronic resource]
Producer: 19980909Description: 3276-92 p. digitalISSN:- 0022-2623
- 3T3 Cells
- Animals
- Antineoplastic Agents -- chemical synthesis
- Biotransformation
- Cell Division -- drug effects
- Cisplatin -- therapeutic use
- Enzyme Inhibitors -- chemical synthesis
- Female
- Humans
- Male
- Mice
- Mice, Nude
- Molecular Conformation
- Molecular Structure
- Ovarian Neoplasms -- drug therapy
- Platelet-Derived Growth Factor -- pharmacology
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Pyrimidinones -- chemical synthesis
- Rats
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Structure-Activity Relationship
- Transplantation, Heterologous
- Tumor Cells, Cultured
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Publication Type: Journal Article
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