Hepatic responses to inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase: a comparison of atorvastatin and simvastatin. [electronic resource]
Producer: 19980407Description: 213-21 p. digitalISSN:- 0006-3002
- Animals
- Anticholesteremic Agents -- pharmacology
- Atorvastatin
- Carcinoma, Hepatocellular
- Cholesterol -- biosynthesis
- Enzyme Induction
- Heptanoic Acids -- pharmacology
- Humans
- Hydroxymethylglutaryl CoA Reductases -- biosynthesis
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Kinetics
- Liver -- drug effects
- Liver Neoplasms
- Male
- Pyrroles -- pharmacology
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley
- Simvastatin -- pharmacology
- Transcription, Genetic -- drug effects
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article
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