Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current. [electronic resource]
Producer: 19980521Description: 771-81 p. digitalISSN:- 0022-3751
- Amino Acid Sequence
- Animals
- Arachidonic Acid -- metabolism
- Cats
- Cerebral Arteries -- metabolism
- Cloning, Molecular
- Cytochrome P-450 CYP4A
- Cytochrome P-450 Enzyme System -- biosynthesis
- DNA Primers
- Humans
- Hydroxyeicosatetraenoic Acids -- metabolism
- In Vitro Techniques
- Membrane Potentials -- drug effects
- Mixed Function Oxygenases -- biosynthesis
- Molecular Sequence Data
- Muscle, Smooth, Vascular -- metabolism
- Nifedipine -- pharmacology
- Polymerase Chain Reaction
- RNA, Messenger -- biosynthesis
- Rats
- Sequence Alignment
- Sequence Homology, Amino Acid
- Transcription, Genetic
- Vasoconstriction -- drug effects
- Vasoconstrictor Agents -- pharmacology
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Publication Type: Journal Article
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