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Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current.

Gebremedhin, D

Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current. [electronic resource] - The Journal of physiology Mar 1998 - 771-81 p. digital

Publication Type: Journal Article

ISSN: 0022-3751

Standard No.: 10.1111/j.1469-7793.1998.771bs.x doi

Subjects--Topical Terms:
Amino Acid Sequence
Animals
Arachidonic Acid--metabolism
Cats
Cerebral Arteries--metabolism
Cloning, Molecular
Cytochrome P-450 CYP4A
Cytochrome P-450 Enzyme System--biosynthesis
DNA Primers
Humans
Hydroxyeicosatetraenoic Acids--metabolism
In Vitro Techniques
Membrane Potentials--drug effects
Mixed Function Oxygenases--biosynthesis
Molecular Sequence Data
Muscle, Smooth, Vascular--metabolism
Nifedipine--pharmacology
Polymerase Chain Reaction
RNA, Messenger--biosynthesis
Rats
Sequence Alignment
Sequence Homology, Amino Acid
Transcription, Genetic
Vasoconstriction--drug effects
Vasoconstrictor Agents--pharmacology