Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function. [electronic resource]
Producer: 19980501Description: 43-55 p. digitalISSN:- 0968-0896
- 4-Butyrolactone -- analogs & derivatives
- Animals
- Anticonvulsants -- pharmacology
- Binding, Competitive
- Bridged Bicyclo Compounds, Heterocyclic -- metabolism
- Cells, Cultured
- Convulsants -- pharmacology
- Electrophysiology
- Female
- Fluorine Compounds -- chemical synthesis
- Furans -- chemistry
- GABA Modulators -- pharmacology
- Hippocampus -- drug effects
- Mice
- Neurons -- drug effects
- Picrotoxin -- chemistry
- Rats
- Receptors, GABA-A -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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