Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid. [electronic resource]
Producer: 19980317Description: 420-7 p. digitalISSN:- 0022-2623
- Animals
- Antioxidants -- chemical synthesis
- Arachidonate 5-Lipoxygenase -- metabolism
- Arachidonic Acid -- chemistry
- Cell Line, Transformed
- Cell Nucleus -- metabolism
- Cyclooxygenase 1
- Cyclooxygenase 2
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors -- chemical synthesis
- Drug Design
- Indicators and Reagents
- Isoenzymes -- metabolism
- Lipopolysaccharides -- pharmacology
- Lipoxygenase Inhibitors -- chemical synthesis
- Macrophages, Peritoneal -- drug effects
- Malondialdehyde
- Membrane Proteins
- Models, Molecular
- Molecular Conformation
- Molecular Structure
- NF-kappa B -- metabolism
- Prostaglandin-Endoperoxide Synthases -- metabolism
- Rats
- Structure-Activity Relationship
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Publication Type: Journal Article
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