The synergistic effects of vitamin D metabolites and transforming growth factor-beta on costochondral chondrocytes are mediated by increases in protein kinase C activity involving two separate pathways. [electronic resource]
Producer: 19980218Description: 534-45 p. digitalISSN:- 0013-7227
- 24,25-Dihydroxyvitamin D 3 -- pharmacology
- Alkaline Phosphatase -- metabolism
- Animals
- Calcitriol -- pharmacology
- Cartilage -- cytology
- Cells, Cultured
- Cholera Toxin -- pharmacology
- Chondrocytes -- drug effects
- Diacylglycerol Kinase -- antagonists & inhibitors
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Protein Kinase C -- drug effects
- Pyrimidinones -- pharmacology
- Rats
- Ribs -- drug effects
- Sulfates -- metabolism
- Thiazoles -- pharmacology
- Thymidine -- metabolism
- Transforming Growth Factor beta -- pharmacology
- Virulence Factors, Bordetella -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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