The synergistic effects of vitamin D metabolites and transforming growth factor-beta on costochondral chondrocytes are mediated by increases in protein kinase C activity involving two separate pathways.
Schwartz, Z
The synergistic effects of vitamin D metabolites and transforming growth factor-beta on costochondral chondrocytes are mediated by increases in protein kinase C activity involving two separate pathways. [electronic resource] - Endocrinology Feb 1998 - 534-45 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0013-7227
10.1210/endo.139.2.5753 doi
24,25-Dihydroxyvitamin D 3--pharmacology
Alkaline Phosphatase--metabolism
Animals
Calcitriol--pharmacology
Cartilage--cytology
Cells, Cultured
Cholera Toxin--pharmacology
Chondrocytes--drug effects
Diacylglycerol Kinase--antagonists & inhibitors
Drug Synergism
Enzyme Inhibitors--pharmacology
Protein Kinase C--drug effects
Pyrimidinones--pharmacology
Rats
Ribs--drug effects
Sulfates--metabolism
Thiazoles--pharmacology
Thymidine--metabolism
Transforming Growth Factor beta--pharmacology
Virulence Factors, Bordetella--pharmacology
The synergistic effects of vitamin D metabolites and transforming growth factor-beta on costochondral chondrocytes are mediated by increases in protein kinase C activity involving two separate pathways. [electronic resource] - Endocrinology Feb 1998 - 534-45 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0013-7227
10.1210/endo.139.2.5753 doi
24,25-Dihydroxyvitamin D 3--pharmacology
Alkaline Phosphatase--metabolism
Animals
Calcitriol--pharmacology
Cartilage--cytology
Cells, Cultured
Cholera Toxin--pharmacology
Chondrocytes--drug effects
Diacylglycerol Kinase--antagonists & inhibitors
Drug Synergism
Enzyme Inhibitors--pharmacology
Protein Kinase C--drug effects
Pyrimidinones--pharmacology
Rats
Ribs--drug effects
Sulfates--metabolism
Thiazoles--pharmacology
Thymidine--metabolism
Transforming Growth Factor beta--pharmacology
Virulence Factors, Bordetella--pharmacology