Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis. [electronic resource]
Producer: 19971210Description: 115-26 p. digitalISSN:- 1380-2933
- Amino Acid Sequence
- Antibodies, Monoclonal -- immunology
- Antibody Specificity
- Antigens, CD -- metabolism
- Binding, Competitive
- Cell Line
- Complement C5a -- chemistry
- Enzyme-Linked Immunosorbent Assay
- Epitope Mapping
- Humans
- Mutagenesis, Site-Directed
- Peptide Library
- Receptor, Anaphylatoxin C5a
- Receptors, Complement -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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