Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis.

Kola, A

Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis. [electronic resource] - Immunotechnology : an international journal of immunological engineering Jun 1996 - 115-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1380-2933

10.1016/1380-2933(96)00425-3 doi


Amino Acid Sequence
Antibodies, Monoclonal--immunology
Antibody Specificity
Antigens, CD--metabolism
Binding, Competitive
Cell Line
Complement C5a--chemistry
Enzyme-Linked Immunosorbent Assay
Epitope Mapping
Humans
Mutagenesis, Site-Directed
Peptide Library
Receptor, Anaphylatoxin C5a
Receptors, Complement--metabolism
Structure-Activity Relationship