Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma. [electronic resource]
Producer: 19971017Description: 386-92 p. digitalISSN:- 1044-1549
- Abatacept
- Administration, Inhalation
- Animals
- Antigens, CD
- Antigens, Differentiation -- metabolism
- Asthma -- immunology
- Bronchi -- cytology
- Bronchial Hyperreactivity -- prevention & control
- Bronchoconstrictor Agents -- pharmacology
- CTLA-4 Antigen
- Cytokines -- biosynthesis
- Disease Models, Animal
- Eosinophilia -- immunology
- Immunoconjugates
- Immunoglobulin E -- physiology
- Immunoglobulin G -- metabolism
- Immunosuppressive Agents -- metabolism
- Male
- Methacholine Chloride -- pharmacology
- Mice
- Mice, Inbred BALB C
- Ovalbumin -- immunology
- Protein Binding -- immunology
- Pulmonary Alveoli -- cytology
- Specific Pathogen-Free Organisms
- Spleen -- cytology
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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